The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging - Wikidata - awgldk - TriplyDB

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

http://www.wikidata.org/entity/Q30559277

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Influence of immunoglobulin isotype on therapeutic antibody function Elucidation of monocyte/macrophage dynamics and function by intravital imaging.Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis.Analyses of CD20 monoclonal antibody-mediated tumor cell killing mechanisms: rational design of dosing strategies Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity The Dynamics of Apoptotic Cell Clearance Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.Chemoimmunotherapy for relapsed/refractory and progressive 17p13-deleted chronic lymphocytic leukemia (CLL) combining pentostatin, alemtuzumab, and low-dose rituximab is effective and tolerable and limits loss of CD20 expression by circulating CLL c Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects CD19 as a molecular target in CNS autoimmunity.Neutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells.New agents for the treatment of lymphoid leukemia and lymphoma: focus on recent FDA approvals.Macrophages are critical effectors of antibody therapies for cancer Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma Interactions between Ibrutinib and Anti-CD20 Antibodies: Competing Effects on the Outcome of Combination Therapy.Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms Purification of Plasmodium Sporozoites Enhances Parasite-Specific CD8+ T Cell Responses.Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity."Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production.Natural killer (NK) cells and anti-tumor therapeutic mAb: unexplored interactions.A constant threat for HIV: Fc-engineering to enhance broadly neutralizing antibody activity for immunotherapy of the acquired immunodeficiency syndrome.Impact of Depleting Therapeutic Monoclonal Antibodies on the Host Adaptive Immunity: A Bonus or a Malus?bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.FcγR requirements leading to successful immunotherapy.Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB.Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells Microenvironmental Effects of Cell Death in Malignant Disease.Anti-CD20 monoclonal antibody-dependent phagocytosis of chronic lymphocytic leukaemia cells by autologous macrophages.Maxed out macs: physiologic cell clearance as a function of macrophage phagocytic capacity.Imaging of anticancer drug action in single cells.Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response.Insufficient Innate Immunity Contributes to the Susceptibility of the Castaneous Mouse to Orthopoxvirus Infection.In Vivo Depletion of T Lymphocytes.Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches.Macrophages in the liver prevent metastasis by efficiently eliminating circulating tumor cells after monoclonal antibody immunotherapy.Antibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo.

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P2860

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

http://www.wikidata.org/entity/Q30559277

description

2013 nî lūn-bûn

@nan

2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

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The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

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type

label

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

@ast

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

@en

prefLabel

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

@ast

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

@en

P1433

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P1433

Journal of Clinical Investigation

P1476

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

@en

P2093

Béatrice Breart

http://www.w3.org/2001/XMLSchema#string

Fabricio Montalvao

http://www.w3.org/2001/XMLSchema#string

Nico Van Rooijen

http://www.w3.org/2001/XMLSchema#string

Susanna Celli

http://www.w3.org/2001/XMLSchema#string

Zacarias Garcia

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo.

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity

Monoclonal antibodies: versatile platforms for cancer immunotherapy.

Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma

Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice.

The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy

Mechanisms of killing by anti-CD20 monoclonal antibodies.

Microanatomy of the liver immune system.

P304

5098-5103

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scholarly article

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10.1172/JCI70972

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P433

12

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P478

123

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Philippe Bousso

Jacques Deguine

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2013-11-01T00:00:00Z

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24177426

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P932

3859399

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