The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
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Influence of immunoglobulin isotype on therapeutic antibody functionElucidation of monocyte/macrophage dynamics and function by intravital imaging.Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis.Analyses of CD20 monoclonal antibody-mediated tumor cell killing mechanisms: rational design of dosing strategiesGlycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicityThe Dynamics of Apoptotic Cell ClearanceIbrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.Chemoimmunotherapy for relapsed/refractory and progressive 17p13-deleted chronic lymphocytic leukemia (CLL) combining pentostatin, alemtuzumab, and low-dose rituximab is effective and tolerable and limits loss of CD20 expression by circulating CLL cIntravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodiesAdministration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effectsCD19 as a molecular target in CNS autoimmunity.Neutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells.New agents for the treatment of lymphoid leukemia and lymphoma: focus on recent FDA approvals.Macrophages are critical effectors of antibody therapies for cancerAntibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myelomaInteractions between Ibrutinib and Anti-CD20 Antibodies: Competing Effects on the Outcome of Combination Therapy.Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanismsPurification of Plasmodium Sporozoites Enhances Parasite-Specific CD8+ T Cell Responses.Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity."Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumorsInteraction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinomaObinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production.Natural killer (NK) cells and anti-tumor therapeutic mAb: unexplored interactions.A constant threat for HIV: Fc-engineering to enhance broadly neutralizing antibody activity for immunotherapy of the acquired immunodeficiency syndrome.Impact of Depleting Therapeutic Monoclonal Antibodies on the Host Adaptive Immunity: A Bonus or a Malus?bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.FcγR requirements leading to successful immunotherapy.Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB.Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor CellsMicroenvironmental Effects of Cell Death in Malignant Disease.Anti-CD20 monoclonal antibody-dependent phagocytosis of chronic lymphocytic leukaemia cells by autologous macrophages.Maxed out macs: physiologic cell clearance as a function of macrophage phagocytic capacity.Imaging of anticancer drug action in single cells.Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T CellsTumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response.Insufficient Innate Immunity Contributes to the Susceptibility of the Castaneous Mouse to Orthopoxvirus Infection.In Vivo Depletion of T Lymphocytes.Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches.Macrophages in the liver prevent metastasis by efficiently eliminating circulating tumor cells after monoclonal antibody immunotherapy.Antibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo.
P2860
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P2860
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@ast
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@en
type
label
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@ast
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@en
prefLabel
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@ast
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@en
P2093
P2860
P356
P1476
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
@en
P2093
Béatrice Breart
Fabricio Montalvao
Nico Van Rooijen
Susanna Celli
Zacarias Garcia
P2860
P304
P356
10.1172/JCI70972
P407
P577
2013-11-01T00:00:00Z