The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens.
about
The miRNA world of polyomavirusesBinding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigensIdentification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirusProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingHuman immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2ALinkage mapping of the Bra, Brb and Brg genes for rat protein phosphatase 2A 55 kDa B-regulatory subunit isotypes.Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.Natural biology of polyomavirus middle T antigen.Enumeration of the simian virus 40 early region elements necessary for human cell transformationA cornucopia of human polyomaviruses.Genetic analysis of B55alpha/Cdc55 protein phosphatase 2A subunits: association with the adenovirus E4orf4 protein.Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigenInhibition of PP2A by LIS1 increases HIV-1 gene expression.Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A.Amino-terminal regions of polyomavirus middle T antigen are required for interactions with protein phosphatase 2A.A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.Retroviral cyclin enhances cyclin-dependent kinase-8 activity.Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent mannerAdenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription.Multiple, distinct trans-activation functions are encoded by the simian virus 40 large T and small t antigens, only some of which require the 82-residue amino-terminal common domain.Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.Protein phosphatase 2A is required for the initiation of chromosomal DNA replication.Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55.Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells.Overexpression of simian virus 40 small-T antigen blocks centrosome function and mitotic progression in human fibroblasts.Simian virus 40 small tumor antigen induces deregulation of the actin cytoskeleton and tight junctions in kidney epithelial cells.Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cellsThe 55 kDa regulatory subunit of protein phosphatase 2A plays a role in the activation of the HPV16 long control region in human cells with a deletion in the short arm of chromosome 11.New nucleotide sequence data on the EMBL File Server
P2860
Q21231951-12D2F973-0871-47A9-BEFD-2B538FA96F87Q22008523-6916C7D5-5C2D-42A1-B8CF-33E54B2C04FAQ24337360-68DBE8F9-64D3-4301-A2DA-94F819B36BA9Q24532278-D7D90141-236C-4D04-BBFC-40747AB40FD7Q24630574-FF9A0D3B-EAE3-471E-A929-93D4728B5CACQ31956833-9AA1B3A5-B379-4786-8D07-AF284D2F0123Q33810466-47D7699F-6EDF-4ED6-A3FF-009845DFA0A4Q33948870-B3B763C3-61C8-47DA-8717-C7178C9C4457Q34117528-8DC54BB0-AF0E-4F22-8980-B1E7802CDD04Q34332024-568F7C30-01D3-40E9-92FD-24AACF414EA8Q34458003-38A32ACE-C309-41D6-B49F-7EA02F807976Q34532657-12FF515E-6587-4336-BBE0-032D91EEA3BEQ34675213-788DFCF4-8635-4157-9184-FC450361EFEBQ35098682-D5713FFD-CFDD-449D-8A6B-9319B1E4384AQ35614264-80C7B0BF-66FD-4534-940A-6A64A75860CAQ35839940-339D74BD-8C42-4128-B93F-ADC78A286B90Q35839944-0F2B5999-D4C9-438B-AC39-1D4DC506EA28Q35870456-D1440AE5-3D7B-4DC1-BF70-95382A6F8137Q35943461-4FAE6168-C4FF-4D6C-BE38-9EF64E2AEB76Q36172723-6C04EDEC-73AD-4760-9AAC-A4FD616CFBA2Q36655478-E2ADCBC1-1B1E-43AF-9420-980CBFC5916BQ36655649-88C299DF-2626-4CF7-BF36-3B55987C8C58Q36681859-9ADF6953-CE5A-41D8-AD17-C0C2392BDC5FQ36685985-D088FD28-EBDC-453A-9341-933E12D1D2BFQ36753616-CF3B8946-8F50-46CA-965C-BADDB1041598Q36885712-602ADB4D-AC2C-48A0-823C-E6195A9BF9FEQ39579102-068294EC-EAB1-44D6-9D69-FB1F4AD4CE55Q39604427-DD733723-3356-441A-8D34-A28FC361801EQ39733486-7F6B4CE2-4D1E-4A91-8D8F-1B7C73466ADDQ40021232-BBCD71D0-7506-4834-8E78-3DB72B21CE30Q41086433-55A83C7D-0348-4579-97F4-6D100B2F52BFQ56899473-8EA6A0D9-DA0E-4F1D-9067-4FB2A94480F0
P2860
The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens.
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The third subunit of protein p ...... tle resemblance to T antigens.
@ast
The third subunit of protein p ...... tle resemblance to T antigens.
@en
type
label
The third subunit of protein p ...... tle resemblance to T antigens.
@ast
The third subunit of protein p ...... tle resemblance to T antigens.
@en
prefLabel
The third subunit of protein p ...... tle resemblance to T antigens.
@ast
The third subunit of protein p ...... tle resemblance to T antigens.
@en
P2093
P2860
P1433
P1476
The third subunit of protein p ...... tle resemblance to T antigens.
@en
P2093
P2860
P304
P577
1992-02-01T00:00:00Z