Fluorescent photoaffinity labeling of cytochrome P450 3A4 by lapachenole: identification of modification sites by mass spectrometry.
about
Photoaffinity labeling combined with mass spectrometric approaches as a tool for structural proteomics.Identification of ligand binding site of phytosulfokine receptor by on-column photoaffinity labeling.Covalent modification of Thr302 in cytochrome P450 2B1 by the mechanism-based inactivator 4-tert-butylphenylacetyleneSimultaneous synthesis of both rings of chromenes via a benzannulation/o-quinone methide formation/electrocyclization cascade.Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsReaction of human cytochrome P450 3A4 with peroxynitrite: nitrotyrosine formation on the proximal side impairs its interaction with NADPH-cytochrome P450 reductase.Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5).Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.Conformational plasticity and structure/function relationships in cytochromes P450.Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe.Efficient generation of ortho-naphthoquinone methides from 1,4-epoxy-1,4-dihydronaphthalenes and their annulation with allyl silanes.High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4.
P2860
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P2860
Fluorescent photoaffinity labeling of cytochrome P450 3A4 by lapachenole: identification of modification sites by mass spectrometry.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@ast
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@en
type
label
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@ast
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@en
prefLabel
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@ast
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@en
P2093
P356
P1433
P1476
Fluorescent photoaffinity labe ...... on sites by mass spectrometry.
@en
P2093
Arthur G Roberts
Carlos A Gartner
Catalin E Doneanu
Sidney D Nelson
William M Atkins
P304
P356
10.1021/BI048228C
P407
P577
2005-02-01T00:00:00Z