about
Small molecule tools for functional interrogation of protein tyrosine phosphatasesAn inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell linesConsiderations for designing chemical screening strategies in plant biology.Chemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals.Chemogenomics approaches to novel target discovery.Using small molecules to dissect mechanisms of microbial pathogenesis.A chemical screen for suppressors of the avrRpm1-RPM1-dependent hypersensitive cell death response in Arabidopsis thalianaPredicting the points of interaction of small molecules in the NF-κB pathwayPhenotypic screening of phylomer peptide libraries derived from genome fragments to identify and validate new targets and therapeutics.Chemical genetics identifies small-molecule modulators of neuritogenesis involving neuregulin-1/ErbB4 signaling.Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells.The yeast three-hybrid system as an experimental platform to identify proteins interacting with small signaling molecules in plant cells: potential and limitationsAn inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.Gene expression profiling in the discovery, optimization and development of novel drugs: one universal screening platform.Confronting the scientific obstacles to global control of tuberculosis.Small molecules in an RNAi world.Small and lethal: searching for new antibacterial compounds with novel modes of action.Cell-based apoptosis assays in oncology drug discovery.Exploring the roles of protein kinases using chemical genetics.Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3.A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regenerationInverse drug screens: a rapid and inexpensive method for implicating molecular targets.Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Advances in chemical genetics.
@ast
Advances in chemical genetics.
@en
type
label
Advances in chemical genetics.
@ast
Advances in chemical genetics.
@en
prefLabel
Advances in chemical genetics.
@ast
Advances in chemical genetics.
@en
P1476
Advances in chemical genetics.
@en
P2093
Brent R Stockwell
Inese Smukste
P304
P356
10.1146/ANNUREV.GENOM.6.080604.162136
P577
2005-01-01T00:00:00Z