Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
about
Automatic NMR-based identification of chemical reaction types in mixtures of co-occurring reactionsClustering Based on Periodicity in High-Throughput Time Course Data.So what have data standards ever done for us? The view from metabolomics.Metabolic profiles in serum of mouse after chronic exposure to drinking water.Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology.Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics.Metabolomics in toxicology and preclinical research.A Predictive Model for Toxicity Effects Assessment of Biotransformed Hepatic Drugs Using Iterative Sampling Method.The role of metabolic biomarkers in drug toxicity studies.Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy.Metabolomics for early detection of drug-induced kidney injury: review of the current status.Metabonomics approaches and the potential application in foodsafety evaluation.Toward predictive models for drug-induced liver injury in humans: are we there yet?The impact of DNA methylation technologies on drug toxicology.Metabolic phenotyping applied to pre-clinical and clinical studies of acetaminophen metabolism and hepatotoxicity.Development of novel tools for the in vitro investigation of drug-induced liver injury.Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury.VIZR--an automated chemometric technique for metabolic profiling.Time-resolved metabolic footprinting for nonlinear modeling of bacterial substrate utilization.An integrative approach for identifying a metabolic phenotype predictive of individualized pharmacokinetics of tacrolimus.High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues.Genetic algorithms for simultaneous variable and sample selection in metabonomics.Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies.Mixed learning algorithms and features ensemble in hepatotoxicity prediction.Integrated histopathological and urinary metabonomic investigation of the pathogenesis of microcystin-LR toxicosis.In silico toxicity prediction by support vector machine and SMILES representation-based string kernel.Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.Investigating sources of variability in metabolomic data in the EPIC study: the Principal Component Partial R-square (PC-PR2) methodZebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury
P2860
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P2860
Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Prediction and classification ...... toxicology screening approach.
@ast
Prediction and classification ...... toxicology screening approach.
@en
Prediction and classification ...... toxicology screening approach.
@nl
type
label
Prediction and classification ...... toxicology screening approach.
@ast
Prediction and classification ...... toxicology screening approach.
@en
Prediction and classification ...... toxicology screening approach.
@nl
prefLabel
Prediction and classification ...... toxicology screening approach.
@ast
Prediction and classification ...... toxicology screening approach.
@en
Prediction and classification ...... toxicology screening approach.
@nl
P2093
P356
P1476
Prediction and classification ...... toxicology screening approach.
@en
P2093
Elaine Holmes
Hector C Keun
John C Lindon
Mary E Bollard
Olaf P Beckonert
Timothy M D Ebbels
P304
P356
10.1021/PR0703021
P577
2007-10-04T00:00:00Z