A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPARγ partial agonists
about
Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validationAnalysis of structure-based virtual screening studies and characterization of identified active compounds.A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.IVSPlat 1.0: an integrated virtual screening platform with a molecular graphical interface.Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways.Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors.PL-PatchSurfer2: Improved Local Surface Matching-Based Virtual Screening Method That Is Tolerant to Target and Ligand Structure Variation.Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode.Probing the S1' site for the identification of non-zinc-binding MMP-2 inhibitors.Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery
P2860
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P2860
A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPARγ partial agonists
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A combined ligand- and structu ...... romolar PPARγ partial agonists
@ast
A combined ligand- and structu ...... romolar PPARγ partial agonists
@en
type
label
A combined ligand- and structu ...... romolar PPARγ partial agonists
@ast
A combined ligand- and structu ...... romolar PPARγ partial agonists
@en
prefLabel
A combined ligand- and structu ...... romolar PPARγ partial agonists
@ast
A combined ligand- and structu ...... romolar PPARγ partial agonists
@en
P2093
P2860
P356
P1433
P1476
A combined ligand- and structu ...... romolar PPARγ partial agonists
@en
P2093
Dušica Vidović
Patrick R Griffin
Scott A Busby
Stephan C Schürer
P2860
P304
P356
10.1002/CMDC.201000428
P577
2011-01-01T00:00:00Z