Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations. - Wikidata - awgldk - TriplyDB

Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.

Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.

http://www.wikidata.org/entity/Q33797492

about

Mammalian Krüppel-like factors in health and diseases The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening Intersection of AHR and Wnt signaling in development, health, and disease.Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells.Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer.More than two decades of Apc modeling in rodents A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).Role of Krüppel-like factors in cancer stem cells.Krüppel-like factors in hepatocellular carcinoma.Krüppel-like factors in mammalian stem cells and development.Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon.SP and KLF Transcription Factors in Digestive Physiology and Diseases.Improved Swiss-rolling Technique for Intestinal Tissue Preparation for Immunohistochemical and Immunofluorescent Analyses.Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.Aging and the Krüppel-like factors.KLF5 mediates the hyper-proliferative phenotype of the intestinal epithelium in mice with intestine-specific endogenous K-RasG12D expression.

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Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.

http://www.wikidata.org/entity/Q33797492

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

@wuu

name

Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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type

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Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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prefLabel

Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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Molecular Cancer

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Krüppel-like factor 5 is a cru ...... ApcMin and KRASV12 mutations.

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P2093

Amr M Ghaleb

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Beth B McConnell

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Mandayam O Nandan

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Nilesh V Patel

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Sylvie Robine

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Vincent W Yang

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P2860

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation

The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology

Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

A genetic model for colorectal tumorigenesis

The consensus coding sequences of human breast and colorectal cancers

The genomic landscapes of human breast and colorectal cancers

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10.1186/1476-4598-9-63

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9

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