The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.
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Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological TargetsFalstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasionVinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug DesignStructures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity ‡Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparumBiochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4The Ionic and hydrophobic interactions are required for the auto activation of cysteine proteases of Plasmodium falciparumStructural basis for unique mechanisms of folding and hemoglobin binding by a malarial proteaseGenetic and structural characterization of PvSERA4: potential implication as therapeutic target for Plasmodium vivax malaria.Cross-talk between malarial cysteine proteases and falstatin: the BC loop as a hot-spot target.Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparumEngineering Nucleotide Specificity of Succinyl-CoA Synthetase in Blastocystis: The Emerging Role of Gatekeeper ResiduesA cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic developmentCentenary celebrations article: Cysteine proteases of human malaria parasites.Structure-function of falcipains: malarial cysteine proteases.Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasitesEfficient expression systems for cysteine proteases of malaria parasites: too good to be true?Target identification and validation of novel antimalarials.Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents.Role of Proteases in Chronic Obstructive Pulmonary Disease.Falcipain-1, a Plasmodium falciparum cysteine protease with vaccine potentialDynamical footprint of falcipain-2 catalytic triad in hemoglobin-β-bound state.Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid.Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead.CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts--a bioinformatical analysis.Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association with Artemisinin Resistance.Allosteric Site Inhibitor Disrupting Auto-Processing of Malarial Cysteine Proteases
P2860
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P2860
The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@ast
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@en
type
label
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@ast
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@en
prefLabel
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@ast
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@en
P2093
P2860
P356
P1476
The Plasmodium falciparum cyst ...... emoglobin, via a unique motif.
@en
P2093
Anthony L Lau
Kailash C Pandey
Puran S Sijwali
Stephanie X Wang
P2860
P304
P356
10.1073/PNAS.0502368102
P407
P577
2005-06-17T00:00:00Z