The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.
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Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatelliteTherapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingSpanning the genomics era: the vital role of a single institution biorepository for childhood cancer research over a decadeThe second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex diseaseTwenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward?Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesExploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic targetComplete loss of STAG2 expression is an indicator of good prognosis in patients with bladder cancer.Recent advances in targeted therapy for Ewing sarcomaMicroRNAs in the pathobiology of sarcomasEvaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue SarcomasThe endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma.Clinicopathologic features of a second patient with Ewing-like sarcoma harboring CIC-FOXO4 gene fusion.Bone- and cartilage-forming tumors and ewing sarcoma: an update with a gnathic emphasis.Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.Detection of EWS/FLI-1 fusion in non-Ewing soft tissue tumors.Targeted therapies for advanced Ewing sarcoma family of tumors.Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent SequencingThe role of FLI-1-EWS, a fusion gene reciprocal to EWS-FLI-1, in Ewing sarcoma.Identification of Novel Fusion Genes in Testicular Germ Cell Tumors.Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.The three-dimensional cancer genome.Osteosarcoma With Apparent Ewing Sarcoma Gene Rearrangement.Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISHGene fusions in soft tissue tumors: Recurrent and overlapping pathogenetic themes18F-FLT Positron Emission Tomography (PET) is a Pharmacodynamic Marker for EWS-FLI1 Activity and Ewing Sarcoma.RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma.CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression.Cancer genomics: why rare is valuable.DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.Massive parallel sequencing in sarcoma pathobiology: state of the art and perspectives.EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma.Next steps in Ewing sarcoma (epi-)genomics.Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice
P2860
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P1343
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P2860
The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@ast
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@en
type
label
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@ast
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@en
prefLabel
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@ast
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@en
P2093
P2860
P4510
P50
P1433
P1476
The genomic landscape of the E ...... eals recurrent STAG2 mutation.
@en
P2093
Andrew E Horvai
Antonio Llombart-Bosch
Daniel Catchpool
Daniel H Wai
David A Solomon
Hongling Liao
Isidro Machado
Jack F Shern
Javed Khan
Jianjun Wang
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004475
P577
2014-07-10T00:00:00Z