Env-derived gp55 gene of Friend spleen focus-forming virus specifically induces neoplastic proliferation of erythroid progenitor cells.
about
Activation of the N-terminally truncated form of the Stk receptor tyrosine kinase Sf-Stk by Friend virus-encoded gp55 is mediated by cysteine residues in the ecotropic domain of gp55 and the extracellular domain of Sf-Stk.Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsCooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation.Helix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus.Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia.Friend Spleen Focus-Forming Virus Activates the Tyrosine Kinase sf-Stk and the Transcription Factor PU.1 to Cause a Multi-Stage Erythroleukemia in Mice.The noncoding and surface envelope coding sequences of myeloblastosis-associated virus are respectively responsible for nephroblastoma development and renal hyperplasia.Spi-1/PU.1 transgenic mice develop multistep erythroleukemias.Selectable retrovirus vectors encoding Friend virus gp55 or erythropoietin induce polycythemia with different phenotypic expression and disease progression.A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.Distinct superinfection interference properties yet similar receptor utilization by cytopathic and noncytopathic feline leukemia viruses.The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein.Multi-stage Friend murine erythroleukemia: molecular insights into oncogenic cooperation.Association of endogenous retroviruses and long terminal repeats with human disorders.Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line.Characterization of envelope glycoprotein mutants for human T-cell leukemia virus type 1 infectivity and immortalizationA mouse erythroleukemia cell line possessing friend spleen focus-forming virus gp55 transgene and temperature-sensitive mutant p53 gene.Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.
P2860
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P2860
Env-derived gp55 gene of Friend spleen focus-forming virus specifically induces neoplastic proliferation of erythroid progenitor cells.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@ast
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@en
type
label
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@ast
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@en
prefLabel
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@ast
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@en
P2093
P2860
P1433
P1476
Env-derived gp55 gene of Frien ...... of erythroid progenitor cells.
@en
P2093
Nagayoshi M
Watanabe N
P2860
P304
P407
P577
1990-07-01T00:00:00Z