about
The invariant uridine of stop codons contacts the conserved NIKSR loop of human eRF1 in the ribosomeInvariant amino acids essential for decoding function of polypeptide release factor eRF1.Termination of translation: interplay of mRNA, rRNAs and release factors?mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAGViable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiaeCommon and specific amino acid residues in the prokaryotic polypeptide release factors RF1 and RF2: possible functional implicationsNon-Standard Genetic Codes Define New Concepts for Protein EngineeringCrystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switchStop codon recognition in ciliates: Euplotes release factor does not respond to reassigned UGA codonA mechanism for stop codon recognition by the ribosome: a bioinformatic approach.RNA plasticity and selectivity applicable to therapeutics and novel biosensor developmentStructural characterization of eRF1 mutants indicate a complex mechanism of stop codon recognitionIn vitro selection for sense codon suppressionMolecular mechanism of stop codon recognition by eRF1: a wobble hypothesis for peptide anticodons.Polypeptide release at sense and noncognate stop codons by localized charge-exchange alterations in translational release factors.tRNA mimicry in translation termination and beyond.Pyrrolysine and selenocysteine use dissimilar decoding strategies.Omnipotent decoding potential resides in eukaryotic translation termination factor eRF1 of variant-code organisms and is modulated by the interactions of amino acid sequences within domain 1.Three distinct peptides from the N domain of translation termination factor eRF1 surround stop codon in the ribosome.Mouse GSPT2, but not GSPT1, can substitute for yeast eRF3 in vivo.Class I release factors in ciliates with variant genetic codesA tripeptide discriminator for stop codon recognition.HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG.Ratchet-like movements between the two ribosomal subunits: their implications in elongation factor recognition and tRNA translocation.Protein tRNA mimicry in translation termination.An mRNA sequence derived from the yeast EST3 gene stimulates programmed +1 translational frameshifting.Class-1 translation termination factors: invariant GGQ minidomain is essential for release activity and ribosome binding but not for stop codon recognitionConvergence and constraint in eukaryotic release factor 1 (eRF1) domain 1: the evolution of stop codon specificity.Stop codon selection in eukaryotic translation termination: comparison of the discriminating potential between human and ciliate eRF1sAntizyme frameshifting as a functional probe of eukaryotic translational termination.Distinct eRF3 requirements suggest alternate eRF1 conformations mediate peptide release during eukaryotic translation termination.Conversion of omnipotent translation termination factor eRF1 into ciliate-like UGA-only unipotent eRF1.Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast.The polypeptide chain release factor eRF1 specifically contacts the s(4)UGA stop codon located in the A site of eukaryotic ribosomes.The GTP-binding release factor eRF3 as a key mediator coupling translation termination to mRNA decay.Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release.A peptide chain release factor 2 affects the stability of UGA-containing transcripts in Arabidopsis chloroplasts.Cultured bloodstream Trypanosoma brucei adapt to life without mitochondrial translation release factor 1.Ribosomal protein L11 mutations in two functional domains equally affect release factors 1 and 2 activity.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Mimicry grasps reality in translation termination.
@ast
Mimicry grasps reality in translation termination.
@en
type
label
Mimicry grasps reality in translation termination.
@ast
Mimicry grasps reality in translation termination.
@en
prefLabel
Mimicry grasps reality in translation termination.
@ast
Mimicry grasps reality in translation termination.
@en
P2093
P1433
P1476
Mimicry grasps reality in translation termination.
@en
P2093
P304
P356
10.1016/S0092-8674(00)80845-4
P407
P577
2000-05-01T00:00:00Z