Focal adhesion kinase is involved in mechanosensing during fibroblast migration. - Wikidata - awgldk - TriplyDB

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

http://www.wikidata.org/entity/Q33944467

about

beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6 Mechanochemical regulation of growth cone motility Mechanotransduction and extracellular matrix homeostasis The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.The focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxis Stretch-induced stress fiber remodeling and the activations of JNK and ERK depend on mechanical strain rate, but not FAK Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes Non-muscle myosin II takes centre stage in cell adhesion and migration The interplay between cell signalling and mechanics in developmental processes Epidermal growth factor activates the Rho GTPase-activating protein (GAP) Deleted in Liver Cancer 1 via focal adhesion kinase and protein phosphatase 2A Role of surface chemistry in protein remodeling at the cell-material interface Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies Mechanism of Focal Adhesion Kinase Mechanosensing Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation Effects of cell tension on the small GTPase Rac Actin cap associated focal adhesions and their distinct role in cellular mechanosensing Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact Adhesions FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm Optical measurement of arterial mechanical properties: from atherosclerotic plaque initiation to rupture.Tissue stiffness dictates development, homeostasis, and disease progression.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration.Lateral shear forces applied to cells with single elastic micropillars to influence focal adhesion dynamics.The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.Substrate rigidity regulates the formation and maintenance of tissues.Cellular responses to substrate topography: role of myosin II and focal adhesion kinase.Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly.Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking.Localized application of mechanical and biochemical stimuli in 3-D culture.Neutrophil morphology and migration are affected by substrate elasticity.Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.

P2860

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P2860

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

http://www.wikidata.org/entity/Q33944467

description

2001 nî lūn-bûn

@nan

2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@ast

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@en

type

label

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@ast

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@en

prefLabel

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@ast

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@en

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Focal adhesion kinase is involved in mechanosensing during fibroblast migration.

@en

P2093

H B Wang

http://www.w3.org/2001/XMLSchema#string

M Dembo

http://www.w3.org/2001/XMLSchema#string

S K Hanks

http://www.w3.org/2001/XMLSchema#string

Y Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

Cell movement is guided by the rigidity of the substrate.

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

FAK integrates growth-factor and integrin signals to promote cell migration

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

Integrins: emerging paradigms of signal transduction

P304

11295-11300

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scholarly article

P356

10.1073/PNAS.201201198

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P407

P433

20

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P478

98

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2001-09-01T00:00:00Z

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11775294

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P698

11572981

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P921

mechanosensation

P932

58723

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