Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor ex
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The Role of PPARs in CancerComparative analysis of gene regulation by the transcription factor PPARalpha between mouse and humanDietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expressionApolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activatorsCYP4 enzymes as potential drug targets: focus on enzyme multiplicity, inducers and inhibitors, and therapeutic modulation of 20-hydroxyeicosatetraenoic acid (20-HETE) synthase and fatty acid ω-hydroxylase activitiesCross-species gene expression analysis of species specific differences in the preclinical assessment of pharmaceutical compoundsClofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs.Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4.Liver fatty acid-binding protein targets fatty acids to the nucleus. Real time confocal and multiphoton fluorescence imaging in living cells.Induction of overlapping genes by fasting and a peroxisome proliferator in pigs: evidence of functional PPARalpha in nonproliferating species.Gene expression profiles in fathead minnow exposed to 2,4-DNT: correlation with toxicity in mammals.Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles.PPARs, Obesity, and InflammationIdentification of genes related to beak deformity of chickens using digital gene expression profilingCytochrome P450 and xenobiotic receptor humanized mice.Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipasePPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans.PPAR-alpha effects on the heart and other vascular tissues.Genomics and the search for novel biomarkers in toxicology.Tissue-selective, bidirectional regulation of PEX11 alpha and perilipin genes through a common peroxisome proliferator response element.Genetic-dependency of peroxisomal cell functions - emerging aspects.Effect of a Large Dose of Di (2-ethylhexyl) phthalate (DEHP) on Hepatic Peroxisome in Cynomolgus Monkeys (Macaca Fascicularis).PPARalpha agonist-induced rodent tumors: modes of action and human relevance.Peroxisomes in Different Skeletal Cell Types during Intramembranous and Endochondral Ossification and Their Regulation during Osteoblast Differentiation by Distinct Peroxisome Proliferator-Activated Receptors.Application of genomics in preclinical drug safety evaluation.Investigational PPAR-gamma agonists for the treatment of Type 2 diabetes.Cross-species comparative toxicogenomics as an aid to safety assessment.The PPAR-alpha activator fenofibrate fails to provide myocardial protection in ischemia and reperfusion in pigs.Role of signalling systems in the effects of dietary factors on the expression of mammalian CYPs.Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospectivePeroxisome degradation in mammals: mechanisms of action, recent advances, and perspectivesHuman cytochrome p450 family 4 enzymes: function, genetic variation and regulation.Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model.Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.The evolution of gene expression studies in drug safety assessment.Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.IL-6 cooperates with peroxisome proliferator-activated receptor-α-ligands to induce liver fatty acid binding protein (LFABP) up-regulation.TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.Acyl-coenzyme A oxidases 1 and 3 in brown trout (Salmo trutta f. fario): Can peroxisomal fatty acid β-oxidation be regulated by estrogen signaling?
P2860
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P2860
Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor ex
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Differential gene regulation i ...... ly of the level of receptor ex
@ast
Differential gene regulation i ...... ly of the level of receptor ex
@en
type
label
Differential gene regulation i ...... ly of the level of receptor ex
@ast
Differential gene regulation i ...... ly of the level of receptor ex
@en
prefLabel
Differential gene regulation i ...... ly of the level of receptor ex
@ast
Differential gene regulation i ...... ly of the level of receptor ex
@en
P2093
P2860
P356
P1476
Differential gene regulation i ...... ly of the level of receptor ex
@en
P2093
Lawrence JW
Umbenhauer DR
P2860
P304
31521-31527
P356
10.1074/JBC.M103306200
P407
P577
2001-06-19T00:00:00Z