IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.
about
Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cellsEstrogen signaling crosstalk: Implications for endocrine resistance in ovarian cancer.MiR-23a facilitates the replication of HSV-1 through the suppression of interferon regulatory factor 1.Fulvestrant-induced cell death and proteasomal degradation of estrogen receptor α protein in MCF-7 cells require the CSK c-Src tyrosine kinase.miR-23a targets interferon regulatory factor 1 and modulates cellular proliferation and paclitaxel-induced apoptosis in gastric adenocarcinoma cells.Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fateRadiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestineThe Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer.RelA-Induced Interferon Response Negatively Regulates ProliferationSynthetic lethality of PARP inhibition in BRCA-network disrupted tumor cells is associated with interferon pathway activation and enhanced by interferon-γ.The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistanceAnti-cancer effect of Annona Muricata Linn Leaves Crude Extract (AMCE) on breast cancer cell lineNodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis.Endocrine resistance in breast cancer--An overview and update.IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function.GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells.Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.PHENOTYPIC CHARACTERIZATION OF BREAST INVASIVE CARCINOMA VIA TRANSFERABLE TISSUE MORPHOMETRIC PATTERNS LEARNED FROM GLIOBLASTOMA MULTIFORME.Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancerIntracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line.Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2--implications for a combinatorial treatment.IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.Role of STAT1 in the breast.Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway.Transcriptional profile of breast muscle in heat stressed layers is similar to that of broiler chickens at control temperature.BRCA1-mimetic compound NSC35446.HCl inhibits IKKB expression by reducing estrogen receptor-α occupancy in the IKKB promoter and inhibits NF-κB activity in antiestrogen-resistant human breast cancer cells.Interferon regulatory factor 1 inactivation in human cancer.Interferon γ suppresses dentin sialophosphoprotein in oral squamous cell carcinoma cells resulting in antitumor effects, via modulation of the endoplasmic reticulum responseMolecular mechanism of activated T cells in breast cancerEnhanced mitochondrial pyruvate transport elicits a robust ROS production to sensitize the antitumor efficacy of interferon-γ in colon cancer
P2860
Q33702231-4B5746D9-4751-40F9-9039-1A83829BBB85Q34022694-1353300D-A592-47E6-8DFA-EDD74E009BBBQ34612130-1B713675-047F-4EB7-8361-346896DC730DQ34674316-FE87D668-7963-479B-AD71-CBB1D2BF5EF6Q34778619-689C00C4-B27D-4020-8418-2FAA3EA6AFB4Q35178371-4B6F7EE9-AB3D-4FFC-966A-4AE2493FDDAAQ35186424-E06F4F9B-A3D0-4763-9724-976FED0E70C1Q35684410-4D704C0C-837C-4851-B2EC-5D0B24A24A9EQ35804406-C525B460-1691-49C9-9C44-8CB30C133711Q35879098-B4E05E03-AE61-439D-AB34-DD92C873B165Q36013029-2D694BC0-AB4E-4E2B-AA2B-6F4164CF641FQ36112190-72600CDF-5DE8-4593-B5AB-AC747EC1C4B0Q36245954-A5BFDCFB-A4EE-4DB2-BB02-91F9F0E4586BQ36386322-5D3E467C-347C-4C2E-9B0D-942C3656AE41Q36662334-2ED2BF42-A25A-4FD9-BE35-79B5FA63D4F8Q36759341-25E96066-6C75-443C-9485-68C9385AD344Q36850338-2234837B-05C6-4EC5-8F1A-F3F44D265C73Q37064818-2BFB23DC-756E-4FD9-A48D-CEBB0E02208BQ37072811-2C29F784-8B3C-4A9C-AFF5-4ED87A1D6469Q37718357-78364E1B-9835-4558-9E58-6B906C7CAA01Q38326844-012D5E78-6F8C-4D66-BCA1-F77AA8C58580Q38868257-BD2BF665-9F81-4BCE-983D-078380251E75Q38870837-F63162F4-6E42-41AF-8CDF-C991DACCA605Q41389851-0128CF40-A0A5-4F38-AA38-45336A9F2188Q41550398-7D8B3C76-4FC8-4BE5-9A38-613F1B1F34B9Q41696188-5CD7A153-CAC6-486E-B940-2B1BDAC12AE2Q42777355-D6DB6439-76B8-43A7-9D11-FFA008FAF661Q55162579-3C30A9E8-8673-4E64-A192-A5DF31115528Q57478301-57F539EF-CF2B-4450-A672-7A86DCCBA472Q58735629-2A0E2918-6D95-43AE-A36E-C358EA63F11EQ59129711-05E0ED40-F26E-4F38-AC6D-8DB89759464D
P2860
IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@ast
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@en
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@nl
type
label
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@ast
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@en
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@nl
prefLabel
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@ast
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@en
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@nl
P2093
P2860
P1476
IFNgamma restores breast cance ...... o caspase-dependent apoptosis.
@en
P2093
Alan Zwart
Haniee Chung
Jennifer E Mulla
Rebecca B Riggins
Robert Clarke
Yanxia Ning
P2860
P304
P356
10.1158/1535-7163.MCT-09-1169
P577
2010-05-01T00:00:00Z