Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes.
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Fatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicityEvidence for altered thiamine metabolism in diabetes: Is there a potential to oppose gluco- and lipotoxicity by rational supplementation?Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjectsSerum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetesInflammation in the pathogenesis of microvascular complications in diabetes.Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathyMultiplex analysis of age-related protein and lipid modifications in human Bruch's membraneDifferential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice.Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study.Increased DNA dicarbonyl glycation and oxidation markers in patients with type 2 diabetes and link to diabetic nephropathy.Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress.Methylglyoxal-derived hydroimidazolone residue of plasma protein can behave as a predictor of prediabetes in Spontaneously Diabetic Torii rats.The impact of thiamine treatment in the diabetes mellitus.Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?Myoglobin-H2O2 catalyzes the oxidation of β-ketoacids to α-dicarbonyls: mechanism and implications in ketosisDicarbonyls and glyoxalase in disease mechanisms and clinical therapeuticsThiamine and its phosphate esters in relation to cardiometabolic risk factors in Saudi Arabs.How Can Diet Affect the Accumulation of Advanced Glycation End-Products in the Human Body?Health effects of dietary Maillard reaction products: the results of ICARE and other studies.Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect.Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease.Diabetic neuropathy: cellular mechanisms as therapeutic targets.Current therapeutic interventions in the glycation pathway: evidence from clinical studies.The beneficial role of thiamine in Parkinson disease.Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology.Dicarbonyl proteome and genome damage in metabolic and vascular disease.Mass spectrometric determination of early and advanced glycation in biology.Quantitative assessment of organ distribution of dietary protein-bound (13) C-labeled N(ɛ) -carboxymethyllysine after a chronic oral exposure in mice.Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates.Effects of combined dietary chromium(III) propionate complex and thiamine supplementation on insulin sensitivity, blood biochemical indices, and mineral levels in high-fructose-fed rats.Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation.Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.Methylglyoxal and carboxyethyllysine reduce glutamate uptake and S100B secretion in the hippocampus independently of RAGE activation.Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET).Benfotiamine enhances antioxidant defenses and protects against cisplatin-induced DNA damage in nephrotoxic rats.Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease.Increased peritoneal damage in glyoxalase 1 knock-down mice treated with peritoneal dialysis.
P2860
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P2860
Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Increased protein damage in re ...... py in a rat model of diabetes.
@ast
Increased protein damage in re ...... py in a rat model of diabetes.
@en
Increased protein damage in re ...... py in a rat model of diabetes.
@nl
type
label
Increased protein damage in re ...... py in a rat model of diabetes.
@ast
Increased protein damage in re ...... py in a rat model of diabetes.
@en
Increased protein damage in re ...... py in a rat model of diabetes.
@nl
prefLabel
Increased protein damage in re ...... py in a rat model of diabetes.
@ast
Increased protein damage in re ...... py in a rat model of diabetes.
@en
Increased protein damage in re ...... py in a rat model of diabetes.
@nl
P2093
P1433
P1476
Increased protein damage in re ...... py in a rat model of diabetes.
@en
P2093
N Karachalias
P J Thornalley
R Babaei-Jadidi
P2888
P304
P356
10.1007/S00125-010-1722-Z
P577
2010-04-06T00:00:00Z
P5875
P6179
1011505338