Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies
about
A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia FormationCell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre NetworkN-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axisADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo.A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.Modeling extracellular matrix reorganization in 3D environments.The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.Critical role of transient activity of MT1-MMP for ECM degradation in invadopodiaGene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasisDynamic regulation of a cell adhesion protein complex including CADM1 by combinatorial analysis of FRAP with exponential curve-fitting.The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation.RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype.MMP-14 in skeletal muscle repair.Hepatoma-derived growth factor promotes growth and metastasis of hepatocellular carcinoma cells.Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro.Spatial uncertainty modeling of fuzzy information in images for pattern classification.Exosome secretion is enhanced by invadopodia and drives invasive behavior.Spatial chaos and complexity in the intracellular space of cancer and normal cellsMathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases.RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology.Finding Solvable Units of Variables in Nonlinear ODEs of ECM Degradation Pathway Network.Control and inhibition analysis of complex formation processes.MMP Secretion Rate and Inter-invadopodia Spacing Collectively Govern Cancer Invasiveness.ECM Cross-Linking Regulates Invadopodia Dynamics.A cell surface display fluorescent biosensor for measuring MMP14 activity in real-time.
P2860
Q27309256-059C668A-252D-4D61-B835-8049098948FCQ27317341-8EB1838D-C21B-4313-B92E-67D680D6CBD9Q30527787-CA16B53F-335D-4543-82D3-3FC4AE9AD6C2Q30536784-5529B373-31CB-49D9-BA48-7C054A9C9C99Q30575182-2B4F9560-8508-4086-9177-55CC2AF01C0BQ30584664-66C645AD-5342-40D5-901B-BC83ABB0FC4EQ34558272-66B6279E-00CB-4BDD-B2D6-EBB7999A999FQ34575045-60A6F215-D55A-4961-8A0B-DF5D41BCF465Q34758204-D9C80123-9D26-4301-8EA8-0DD8C00C52A3Q35146386-32D265E8-6BF2-4047-B804-E0ED221E41B3Q35579299-680771FF-06AD-40BB-81A6-C1B4839218D1Q37046915-4D40D2DE-1F08-42FA-BC01-3332768E284DQ37061758-4F803E8C-312D-48C9-83EA-52DBCF77B166Q37546037-708DB185-6F64-4B8C-A110-E244698393A0Q37635053-B6277E71-C15C-4053-81FB-A0BC382C2195Q38508171-AB0C636F-CECD-44E3-9BC5-9609AD1CCCD5Q38765991-621EE869-60E7-491D-9C4B-E415B1EA49F9Q38798451-C6E94F37-1CF2-43E9-BD6F-C946C8EBDECDQ38962771-6283E92B-FD62-4F87-A9D0-31397C4BA55BQ39051909-D5241B56-F3C3-41EE-AF30-78E229C2032DQ39072874-B31A22C9-D8CB-4B38-8C48-CCE909C13CB6Q39545421-D8D076FB-6D94-49E7-B260-4680A40F6F69Q41645202-D6EC0EC0-CAE7-4816-B481-E5BEACE81DDCQ41859853-5F1BBEDE-7EB5-4FD5-896E-F879EE69C3DAQ42380747-8D50E655-AED2-475C-843D-BB5BB814B4D1Q50134416-25F98245-36D2-494B-AF7B-996F47F49D3FQ52625345-8F6D499D-00CF-4266-B789-3D6FBBA3D6AAQ54917691-E23B824B-34CC-454D-B266-C56204BAF512
P2860
Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Establishment and validation o ...... on and intervention strategies
@ast
Establishment and validation o ...... on and intervention strategies
@en
Establishment and validation o ...... on and intervention strategies
@nl
type
label
Establishment and validation o ...... on and intervention strategies
@ast
Establishment and validation o ...... on and intervention strategies
@en
Establishment and validation o ...... on and intervention strategies
@nl
prefLabel
Establishment and validation o ...... on and intervention strategies
@ast
Establishment and validation o ...... on and intervention strategies
@en
Establishment and validation o ...... on and intervention strategies
@nl
P2093
P2860
P1476
Establishment and validation o ...... on and intervention strategies
@en
P2093
Daisuke Hoshino
Kazuhisa Ichikawa
Motoharu Seiki
Naohiko Koshikawa
Takashi Suzuki
Vito Quaranta
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002479
P577
2012-04-12T00:00:00Z