The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.
about
Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS developmentEvaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosisAdvances in the characterization of RNA-binding proteinsInside out: the role of nucleocytoplasmic transport in ALS and FTLDEngineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced ActivityThe new (dis)order in RNA regulationDysregulated axonal RNA translation in amyotrophic lateral sclerosisPrion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseImmunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction networkAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Chaperones in NeurodegenerationPathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disordersYeast prions and human prion-like proteins: sequence features and prediction methodsConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisNeuronal RNA-binding proteins in health and diseaseSelf-propagation of pathogenic protein aggregates in neurodegenerative diseasesNeurodegenerative diseases: expanding the prion conceptStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.RNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress responseImpact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI miceStructural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets.Emerging mechanisms of molecular pathology in ALSEngineering enhanced protein disaggregases for neurodegenerative diseaseDeterminants of Amyloid Formation for the Yeast Termination Factor Nab3Are aberrant phase transitions a driver of cellular aging?Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.RNA seeds higher-order assembly of FUS protein.Protein aggregation behavior regulates cyclin transcript localization and cell-cycle controlPrions, amyloids, and RNA: Pieces of a puzzle.The Malignant Protein Puzzle.Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging.Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules.The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity.Sequence search and analysis of gene products containing RNA recognition motifs in the human genome.Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition.Assemblages: functional units formed by cellular phase separationMultistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.RNA metabolism in the pathogenesis of Parkinson׳s disease
P2860
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P2860
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@ast
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@en
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@nl
type
label
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@ast
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@en
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@nl
prefLabel
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@ast
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@en
The tip of the iceberg: RNA-bi ...... in neurodegenerative disease.
@nl
P2860
P921
P1433
P1476
The tip of the iceberg: RNA-bi ...... s in neurodegenerative disease
@en
P2093
Aaron D Gitler
Oliver D King
P2860
P356
10.1016/J.BRAINRES.2012.01.016
P407
P577
2012-01-21T00:00:00Z