Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype.
about
Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder: a systematic review and meta-analysisGenetics of autism spectrum disorderAllelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviorsFactor structure, reliability and criterion validity of the Autism-Spectrum Quotient (AQ): a study in Dutch population and patient groupsGenetics of obsessive-compulsive disorderSupport for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorderFunctional Evaluations of Genes Disrupted in Patients with Tourette's Disorder.Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transportersNetworking in autism: leveraging genetic, biomarker and model system findings in the search for new treatmentsThe serotonergic system in mood disorders and suicidal behaviourA competitive inhibitor traps LeuT in an open-to-out conformation.Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformationRegulation of the serotonin transporter in the pathogenesis of irritable bowel syndromeThe serotonin system in autism spectrum disorder: From biomarker to animal modelsCysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformationPhysical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activityThe Development of Screening Methods to Identify Drugs to Limit ER Stress Using Wild-type and Mutant Serotonin TransporterCharacterization of a functional polymorphism in the 3' UTR of SLC6A4 and its association with drinking intensityEssential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice.How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.Genetic variation in cortico-amygdala serotonin function and risk for stress-related diseaseInvasive circuitry-based neurotherapeutics: stereotactic ablation and deep brain stimulation for OCDInsights from molecular dynamics: the binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters.Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorderBoron-Doped Diamond Microelectrodes Reveal Reduced Serotonin Uptake Rates in Lymphocytes from Adult Rhesus Monkeys Carrying the Short Allele of the 5-HTTLPR.Biological substrates underpinning diagnosis of major depression.Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase.Discovery of novel selective serotonin reuptake inhibitors through development of a protein-based pharmacophore.Discovery of novel-scaffold monoamine transporter ligands via in silico screening with the S1 pocket of the serotonin transporterA neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function.Myristoylation of cGMP-dependent protein kinase dictates isoform specificity for serotonin transporter regulation.Regulation of monoamine transporters: Role of transporter phosphorylation.Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder.A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disordersSignal attenuation as a rat model of obsessive compulsive disorder.Identification of a novel selective serotonin reuptake inhibitor by coupling monoamine transporter-based virtual screening and rational molecular hybridizationQuantitative trait loci mapping and gene network analysis implicate protocadherin-15 as a determinant of brain serotonin transporter expression.Gene-environment interaction and the genetics of depression.Molecular genetics of autism spectrum disorder.
P2860
Q21093204-01315180-C99D-4AE0-9730-FF243F7E8506Q22250993-5D119A67-EF87-4F62-8C81-C0A29E74DACDQ24531235-90CA9BFE-3E17-4AD0-A1B4-2EC9AC36E53FQ24644195-9E8D737D-8EED-4BB8-ACC9-3A6BF5D9B20CQ24645479-0E98D67B-6447-42FB-9FFC-DD0EA3E33736Q24646169-6EF0E8FD-D6B4-422A-A4E8-F350D3B3B01EQ26768144-41188E47-FE35-4EE1-9013-822D0F7C5AD2Q26825537-6471AAE3-9FE3-49FF-8EC3-38E04FBF05BDQ26850307-71B0C7F7-F692-4B62-8C9C-64CE7FF25AA0Q27027537-83CCB464-DE0C-440B-8E0E-7FABB58FA3BBQ27653127-9ADA373A-2CDE-47DF-8786-D35CC4F5F597Q27654242-C84AABE7-58D3-4D09-BBFE-F7D5BB459B4DQ28072085-C3E2017F-ECA0-411F-9F27-A24CB0528107Q28391614-BBC7F02D-DF95-4729-B3CD-07E12467B12BQ28566579-DA5FA766-F002-4436-8A50-E59CC1CF4907Q28593956-4E5113CC-8470-45EE-AB53-0F091A4B5509Q28818314-AE7F924B-350C-4D7D-9F37-3D4369DC873DQ30437148-6880B333-546B-4719-A7E9-B3C22CAC3FBAQ30460205-DDE6E187-4569-4A97-88E4-F77A47567D6FQ30482896-E4AD2936-700F-4E29-9788-5AA0E4C43813Q30485725-11CF80DD-48A4-43D0-B1E1-2F7EF9ABEE30Q30487278-37011544-4F4E-4564-8E1A-9714D9ADAB73Q30498546-50D84C68-4CE5-467A-AD8D-16B8ECEEB925Q30532521-7DBC2D80-9263-492A-AF18-D22369E067A2Q33571104-CEBF107E-C968-450E-9D02-CFEA5881F74CQ33747022-41488600-ACF6-448B-85A4-CE9F5512A93EQ33820463-F5109D17-1700-4585-B120-5EC9B89A28F5Q33913931-BFF4C2D2-23A0-4AE6-B4CC-99D8DEF5ADA7Q33990707-64D7052D-99BC-45DF-8BB4-688DE5E15B1BQ34249476-BCBA4886-C758-4D56-8382-315C0E46711DQ34481155-EF9088C3-2686-4A74-AD42-6A734145769AQ34509255-80A0B5C3-81A2-4B29-84A4-ED4B441592B1Q34540543-E4080D4C-2170-42EA-AF6C-AB5D33906296Q34658088-5AAE249F-7C7B-4958-8649-C5896474937DQ34975117-9AB420D1-6F84-4071-9E68-327950D0475DQ35161903-58F02954-3FD1-4435-9F6E-5D13211EC419Q35234897-DE7E88F5-A2EF-4DEA-819B-337C38B029ACQ35621202-151F9706-A732-411A-83FC-479D151576D4Q35790390-55875DA4-91D0-4CAA-8C9E-5F89C493B049Q35805413-3600C741-04FF-4C0A-A997-050DEEC4BEF5
P2860
Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype.
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@ast
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@en
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@nl
type
label
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@ast
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@en
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@nl
prefLabel
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@ast
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@en
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@nl
P2093
P2860
P356
P1433
P1476
Serotonin transporter missense ...... ex neuropsychiatric phenotype.
@en
P2093
Greenberg BD
Lappalainen J
Plotnicov K
P2860
P2888
P304
P356
10.1038/SJ.MP.4001365
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1004279529