Gene regulation and DNA damage in the ageing human brain.
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Aging and gene expression in the primate brainRule-based cell systems model of aging using feedback loop motifs mediated by stress responsesBreaking news: thinking may be bad for DNAThe endocannabinoid system in normal and pathological brain ageingReplicative senescence induced by Romo1-derived reactive oxygen speciesKnockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsDJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factorCHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genesEvidence by molecular profiling for a placental origin of infantile hemangioma.SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingModeling kinetic rate variation in third generation DNA sequencing data to detect putative modifications to DNA basesThe Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motifCytokines sing the blues: inflammation and the pathogenesis of depressionCoordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase betaMicroRNA: Implications for Alzheimer Disease and other Human CNS DisordersMotif module map reveals enforcement of aging by continual NF-kappaB activityMechanisms of aging in senescence-accelerated miceL2L: a simple tool for discovering the hidden significance in microarray expression dataConsiderations when using the significance analysis of microarrays (SAM) algorithmAging and the environment: a research frameworkMechanisms of FUS mutations in familial amyotrophic lateral sclerosisAge-associated Cognitive Decline: Insights into Molecular Switches and Recovery AvenuesExercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic ShuttleIntegration of 'omics' data in aging research: from biomarkers to systems biologyPrion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage responseImportance and management of micronutrient deficiencies in patients with Alzheimer's diseaseLifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidenceMetabolomics of human brain aging and age-related neurodegenerative diseasesOxidative stress and epilepsy: literature reviewNew cellular and molecular approaches to ageing brainDamaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanismsA PARP1-ERK2 synergism is required for the induction of LTPNovel microRNAs differentially expressed during aging in the mouse brainImpact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family PolymerasesStructural Basis for Error-free Replication of Oxidatively Damaged DNA by Yeast DNA Polymerase ηDietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?REST and stress resistance in ageing and Alzheimer's diseaseCockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodelingStructure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K)Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
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P2860
Gene regulation and DNA damage in the ageing human brain.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Gene regulation and DNA damage in the ageing human brain.
@ast
Gene regulation and DNA damage in the ageing human brain.
@en
Gene regulation and DNA damage in the ageing human brain.
@nl
type
label
Gene regulation and DNA damage in the ageing human brain.
@ast
Gene regulation and DNA damage in the ageing human brain.
@en
Gene regulation and DNA damage in the ageing human brain.
@nl
prefLabel
Gene regulation and DNA damage in the ageing human brain.
@ast
Gene regulation and DNA damage in the ageing human brain.
@en
Gene regulation and DNA damage in the ageing human brain.
@nl
P2093
P2860
P356
P1433
P1476
Gene regulation and DNA damage in the ageing human brain.
@en
P2093
Bruce A Yankner
Jennifer Chan
Shyan-Yuan Kao
P2860
P2888
P304
P356
10.1038/NATURE02661
P407
P50
P577
2004-06-09T00:00:00Z
P5875
P6179
1001579376