Crystal structure of rhodopsin: implications for vision and beyond.
about
Structural approaches to understanding retinal proteins needed for visionChemistry of the retinoid (visual) cycleDrosophila photoreceptor cells exploited for the production of eukaryotic membrane proteins: receptors, transporters and channelsTowards structural systems pharmacology to study complex diseases and personalized medicineChemistry and biology of the initial steps in vision: the Friedenwald lecture.Membrane model for the G-protein-coupled receptor rhodopsin: hydrophobic interface and dynamical structureHow a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.The eye photoreceptor protein rhodopsin. Structural implications for retinal disease.Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors.Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice.The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosaHighly conserved tyrosine stabilizes the active state of rhodopsin.The potential for selective pharmacological therapies through biased receptor signalingG protein-coupled receptor rhodopsin: a prospectus.G protein-coupled receptor rhodopsin.Local peptide movement in the photoreaction intermediate of rhodopsin.Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin.The molecular mechanism of membrane proteins probed by evanescent infrared waves.Solid-state 2H NMR spectroscopy of retinal proteins in aligned membranes.Comparative analysis of GPCR crystal structures.New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.The evolution of vision.Calnexin improves the folding efficiency of mutant rhodopsin in the presence of pharmacological chaperone 11-cis-retinal.An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector.Comparative docking study of anibamine as the first natural product CCR5 antagonist in CCR5 homology models.Purification and biochemical characterization of the D6 chemokine receptorBiased agonism.Differential spatial and temporal phosphorylation of the visual receptor, rhodopsin, at two primary phosphorylation sites in mice exposed to light.Terahertz spectroscopy of bacteriorhodopsin and rhodopsin: similarities and differences.Allosteric theory: taking therapeutic advantage of the malleable nature of GPCRs.The three-dimensional structure of bovine rhodopsin determined by electron cryomicroscopy.A green cone-like pigment in the 'blind' mole-rat Spalax ehrenbergi: functional expression and photochemical characterization.The hydrodynamic properties of dark- and light-activated states of n-dodecyl beta-D-maltoside-solubilized bovine rhodopsin support the dimeric structure of both conformations.Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors.An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
P2860
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P2860
Crystal structure of rhodopsin: implications for vision and beyond.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structure of rhodopsin: implications for vision and beyond.
@ast
Crystal structure of rhodopsin: implications for vision and beyond.
@en
Crystal structure of rhodopsin: implications for vision and beyond.
@nl
type
label
Crystal structure of rhodopsin: implications for vision and beyond.
@ast
Crystal structure of rhodopsin: implications for vision and beyond.
@en
Crystal structure of rhodopsin: implications for vision and beyond.
@nl
prefLabel
Crystal structure of rhodopsin: implications for vision and beyond.
@ast
Crystal structure of rhodopsin: implications for vision and beyond.
@en
Crystal structure of rhodopsin: implications for vision and beyond.
@nl
P1476
Crystal structure of rhodopsin: implications for vision and beyond.
@en
P2093
P304
P356
10.1016/S0959-440X(00)00227-X
P577
2001-08-01T00:00:00Z