Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1 - Wikidata - awgldk - TriplyDB

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

http://www.wikidata.org/entity/Q34338051

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A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration The role of TRPMLs in endolysosomal trafficking and function Mucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaning Regulation of lysosomal ion homeostasis by channels and transporters Mucolipidosis type IV: an update The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel Macroautophagy is defective in mucolipin-1-deficient mouse neurons Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules Heteromerization of TRP channel subunits: extending functional diversity TRP channels Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice The micromachinery of mechanotransduction in hair cells.TRP channels as candidates for hearing and balance abnormalities in vertebrates.Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons Lysosomal trafficking functions of mucolipin-1 in murine macrophages Small molecule activators of TRPML3 Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.Constitutive activity of the human TRPML2 channel induces cell degeneration New insights into TRP channels: Interaction with pattern recognition receptors Calcium signaling via two-pore channels: local or global, that is the question.Transient receptor potential channels and regulation of lung endothelial permeability.Mucolipins: Intracellular TRPML1-3 channels Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.A novel ion channel formed by interaction of TRPML3 with TRPV5.Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs.Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype.Role of TRP channels in the cardiovascular system.Role of protein kinase d in Golgi exit and lysosomal targeting of the transmembrane protein, Mcoln1.Transient receptor potential channels in the vasculature.Role of TRP channels in the regulation of the endosomal pathway.Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.Drosophila TRPML is required for TORC1 activation Novel Role of TRPML2 in the Regulation of the Innate Immune Response Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat.The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function.

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P2860

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

http://www.wikidata.org/entity/Q34338051

description

2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Lysosomal localization of TRPM ...... osis-associated protein TRPML1

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Kartik Venkatachalam

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Thomas Hofmann

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P2860

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV

Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

Association of alpha- and beta-subunits during the biosynthesis of beta-hexosaminidase in cultured human fibroblasts

Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex

Coassembly of TRP and TRPL produces a distinct store-operated conductance

Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner

Subunit composition of mammalian transient receptor potential channels in living cells

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes

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25

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281

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4196876

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