Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.

Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.

Item
http://www.wikidata.org/entity/Q34340537
Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingKDM1 class flavin-dependent protein lysine demethylasesMultimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma.KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1Reversible lysine-specific demethylase 1 antagonist HCI-2509 inhibits growth and decreases c-MYC in castration- and docetaxel-resistant prostate cancer cells.KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.Histone Lysine Demethylase Inhibitors.Epigenetics in endometrial carcinogenesis - part 2: histone modifications, chromatin remodeling and noncoding RNAs.Imiquimod Induces Apoptosis in Human Endometrial Cancer Cells In vitro and Prevents Tumor Progression In vivo.Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies.LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cells.Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
P2860

Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.

Item
http://www.wikidata.org/entity/Q34340537
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@ast
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@en
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@nl
type
label
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@ast
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@en
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@nl
prefLabel
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@ast
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@en
Reversible inhibition of lysin ...... ntiated endometrial carcinoma.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P6179
P698
P932
P356
P1433
P1476
Reversible inhibition of lysin ...... entiated endometrial carcinoma
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P6179
P698
P932