Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.
about
The cell surface environment for pathogen recognition and entryTetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapyRecent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plantsThe role of STIM and ORAI proteins in phagocytic immune cellsThe role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseasesEbolavirus Glycoprotein Directs Fusion through NPC1+ EndolysosomesSystems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional MutagenesisRegulation of lysosomal ion homeostasis by channels and transportersFusion of Enveloped Viruses in Endosomes.Principles of Virus Uncoating: Cues and the Snooker BallStructure of the voltage-gated two-pore channel TPC1 from Arabidopsis thalianaStructure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thalianaEvaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infectionA screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a TriggerSize Dependent Cellular Uptake of Rod-like Bionanoparticles with Different Aspect Ratios.High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heartRecombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis.Molecular mechanisms of Ebola virus pathogenesis: focus on cell death.Function and dysfunction of two-pore channels.Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.Two-Pore Channels: Lessons from Mutant Mouse ModelsTwo-Pore Channels: Catalyzers of Endolysosomal Transport and Function.The human two-pore channel 1 is modulated by cytosolic and luminal calcium.Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor AntagonistsThe Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry InhibitorsNew targets for controlling Ebola virus diseaseIntracellular sphingosine releases calcium from lysosomes.Modulation of Potassium Channels Inhibits Bunyavirus Infection.Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway.TPC2 controls pigmentation by regulating melanosome pH and sizeProphylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection.Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction.Selective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium.Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions.
P2860
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P2860
Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Ebola virus. Two-pore channels ...... targets for disease treatment.
@ast
Ebola virus. Two-pore channels ...... targets for disease treatment.
@en
Ebola virus. Two-pore channels ...... targets for disease treatment.
@nl
type
label
Ebola virus. Two-pore channels ...... targets for disease treatment.
@ast
Ebola virus. Two-pore channels ...... targets for disease treatment.
@en
Ebola virus. Two-pore channels ...... targets for disease treatment.
@nl
prefLabel
Ebola virus. Two-pore channels ...... targets for disease treatment.
@ast
Ebola virus. Two-pore channels ...... targets for disease treatment.
@en
Ebola virus. Two-pore channels ...... targets for disease treatment.
@nl
P2093
P2860
P356
P1433
P1476
Ebola virus. Two-pore channels ...... targets for disease treatment.
@en
P2093
Andrey A Kolokoltsov
Cheng-Chang Chen
Christian Grimm
Christian Wahl-Schott
Martin Biel
Michael W Tidwell
Norbert Klugbauer
Robert A Davey
William E Bauta
Yasuteru Sakurai
P2860
P304
P356
10.1126/SCIENCE.1258758
P407
P577
2015-02-01T00:00:00Z