Myosin VI and optineurin are required for polarized EGFR delivery and directed migration. - Wikidata - awgldk - TriplyDB

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

http://www.wikidata.org/entity/Q34575273

about

Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics Plus-end directed myosins accelerate actin filament sliding by single-headed myosin VI.Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis.Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.Dynamic exchange of myosin VI on endocytic structures Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain Myosin VI facilitates connexin 43 gap junction accretion.Toward an integrative view of Optineurin functions.Myosin VI and its cargo adaptors - linking endocytosis and autophagy.Emerging role of the scaffolding protein Dlg1 in vesicle trafficking.A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity.The Spindle Orientation Machinery Beyond Mitosis: When Cell Specialization Demands Polarization.Myosin VI in PC12 cells plays important roles in cell migration and proliferation but not in catecholamine secretion.Automatic tracking of individual migrating cells using low-magnification dark-field microscopy.MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells.Visual impairment in an optineurin mouse model of primary open-angle glaucoma.MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics.Identification and super-resolution imaging of ligand-activated receptor dimers in live cells.miR-143 and miR-145 inhibit gastric cancer cell migration and metastasis by suppressing MYO6.Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.Myosin VI regulates actin dynamics and melanosome biogenesis.Inducible turnover of optineurin regulates T cell activation.Dock7: a GEF for Rho-family GTPases and a novel myosin VI-binding partner in neuronal PC12 cells.Lipopolysaccharide disrupts the directional persistence of alveolar myofibroblast migration through EGF receptor.Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.

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P2860

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

http://www.wikidata.org/entity/Q34575273

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@ast

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@en

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@nl

type

label

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@ast

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@en

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@nl

prefLabel

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@ast

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@en

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@nl

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P356

J.1600-0854.2010.01101.X

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P1476

Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.

@en

P2093

Alexei Poliakov

http://www.w3.org/2001/XMLSchema#string

Folma Buss

http://www.w3.org/2001/XMLSchema#string

John Kendrick-Jones

http://www.w3.org/2001/XMLSchema#string

Margarita V Chibalina

http://www.w3.org/2001/XMLSchema#string

P2860

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

Myosin VI is an actin-based motor that moves backwards

Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis.

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment.

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries

Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

Cell migration: integrating signals from front to back

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scholarly article

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10.1111/J.1600-0854.2010.01101.X

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10

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11

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