Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification.
about
New antiarrhythmic agents: a conceptually novel approach.Antiarrhythmics--from cell to clinic: past, present, and future.Pharmacology and Toxicology of Nav1.5-Class 1 anti-arrhythmic drugs.Comparison of the electrophysiological effects of Org 7797, disopyramide, mexiletine and propafenone in anaesthetized dogs with myocardial infarcts.Electrophysiological effects of SD-3212, a new antiarrhythmic agent with vasodilator action, on guinea-pig ventricular cells.Differing electrophysiological effects of class IA, IB and IC antiarrhythmic drugs on guinea-pig sinoatrial node.Resting, and rate-dependent depression of Vmax of guinea-pig ventricular action potentials by amiodarone and desethylamiodaroneElectrophysiological effects of melperone on isolated rabbit heart muscles.Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle.Depression of maximum rate of depolarization of guinea-pig ventricular action potentials by metabolites of encainide.Electrophysiological effects of OPC-88117, a new antiarrhythmic agent on papillary muscles and single ventricular myocytes isolated from guinea-pig heartsDifferent time courses of the blockade of sodium current by lignocaine and SUN 1165 in single myocytes isolated from guinea-pig atrium.An electrophysiological comparison of a novel class Ic antiarrhythmic agent, NIK-244 (ethacizin) and flecainide in canine ventricular muscleEffects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium.Electrophysiological effects of diprafenone, a dimethyl congener of propafenone on guinea-pig ventricular cells.Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles.Effects of flecainide on isolated vascular smooth muscles of rat.Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres.Effects of the two enantiomers, S-16257-2 and S-16260-2, of a new bradycardic agent on guinea-pig isolated cardiac preparations.Effects of disopyramide and flecainide on the kinetics of inward rectifier potassium channels in rabbit heart muscleBW A256C, a chemically novel class 1 antiarrhythmic agent. A comparison of in vitro and in vivo activity with other class 1 antiarrhythmic agentsElectrophysiological effects of AFD-21 and AFD-19, new antiarrhythmic compounds on papillary muscles and single ventricular myocytes isolated from guinea-pig hearts.Influence of lorcainide on microsomal Na+, K(+)-ATPase in guinea-pig isolated heart preparationsEffects of bepridil on the electrophysiological properties of guinea-pig ventricular musclesBeta-Adrenergic blockers as antiarrhythmic and antifibrillatory compounds: an overview.Effects of propafenone on calcium currents in single ventricular myocytes of guinea-pig.Kinetics of rate-dependent slowing of intraventricular conduction by the class Ib antiarrhythmic agent tocainide in vivo.A rational scientific basis for subclassification of antiarrhythmic drugsDiscrepant effects of mexiletine on cycle length of ventricular tachycardia and on the effective refractory period in the area of slow conduction.Effects of procainamide and sotalol on restitution properties, dispersion of refractoriness, and ventricular fibrillation activation patterns in pigs.Blocking effect of methylflavonolamine on human Na(V)1.5 channels expressed in Xenopus laevis oocytes and on sodium currents in rabbit ventricular myocytes.Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations.Disopyramide and mianserin intoxication: a unique fatal case--review of the literature.Classification of antiarrhythmic drugs.Encainide: its electrophysiologic and antiarrhythmic effects, pharmacokinetics, and safety.Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.Successful treatment of atrial tachycardias with flecainide acetate.Electromechanical effects of bepridil on rabbit isolated heartsEffects of propafenone on electrical and mechanical activities of single ventricular myocytes isolated from guinea-pig hearts.Can inhibition of IKur promote atrial fibrillation?
P2860
Q33947211-1BFCE65B-6791-4AAA-B482-AB45F3554E6DQ33947683-AB77D933-2876-4A0A-8E57-4D9FC35D1D5FQ34482842-7D07A2DF-9904-4817-A459-46BC621BA8C9Q34708100-D2CDF651-52CD-4D35-AEFE-AB4C6DC85B24Q34792940-9D75C84E-2496-412C-8F4B-F93BF05968DDQ35754771-40B7D0E2-D2C9-47C1-B5A4-5255C4833F0FQ35754950-07CF825A-8821-46B7-81A0-3BD201258EFDQ35755791-D581320F-0001-4A66-B549-BA605F51B8A5Q35756343-1D1653BF-350B-4435-943F-EB291FF30840Q35756498-A2021F40-CA8E-4999-BC46-C886B80C5A90Q35756731-4EC2024C-F928-4932-87D5-1B5E7FC3C34FQ35756758-4094F3EB-1BCC-4A96-863C-9395A153C5D9Q35756878-0844EFE6-3D6E-4516-8D06-79C431A44EE6Q35870956-7785BEFE-EDCB-471B-A777-30F7CAB6C98EQ35871012-140A38D1-0A59-4F44-96EE-2E3E3A9067C5Q35871199-FED65903-5360-4A26-B376-C202058371AEQ35871762-290913D6-7D49-4DA1-8FBD-8BAAB8306A06Q35872072-495D202B-A0DE-4B07-940B-7AEC40D751B9Q35872243-2C31869B-9FC6-480B-B961-518203F9B3CAQ35874425-38F961CD-868B-4A91-9694-5F3461B513A3Q35886893-4650A920-0B28-4DFE-BF1F-59A54C67ADDAQ35888533-62C41E11-D197-45B8-97AF-A2A9FA27A84FQ35888808-76450A28-C7E3-41B3-A72A-C0C7169EB102Q36003639-7247CD71-5452-442F-A7ED-D30F10ED7984Q36167681-1F845E17-B9F1-4B54-BF6F-5233B7356F47Q36329422-60EDD0DC-DE74-4EF5-BEAA-4A8CB72B9E5AQ36330367-3C47464B-6A10-4D5A-B8E3-916AFD0FED30Q36518945-A7023E2A-5623-4C77-A5B4-E3CC5788D552Q36829963-5C8128CB-71D7-48AD-99F9-C63D645D05D5Q37040749-D7CA45AA-EDC3-4FD2-B1A2-B349846938DCQ37728195-EA181CE7-DB3D-402F-B468-D1BB6D53204BQ37755876-70C27D75-B979-4210-93E5-1DE229FE353DQ38185683-87407EE8-B526-49FB-8A52-C506D8A273B6Q38651993-7BAF3C8A-473E-46EB-95B3-DE839E12D8CEQ39600261-D5F4D4A6-56B1-4C07-BDAF-F24152B9EAC5Q40721914-F1E42BD7-0093-4165-8244-0587E43DFFEDQ41308617-7D1D8020-7582-4FC5-819F-EC87A2EB7D57Q41745140-27C8F909-5078-4A1D-A712-6C26EE8BC3CDQ41839851-DDB3E62D-1E15-476D-8F30-96B07921571EQ41880477-E792452F-FC45-4823-8259-DFA1EADB9EE1
P2860
Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification.
description
1983 nî lūn-bûn
@nan
1983 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
name
Kinetics of onset of rate-depe ...... s for their subclassification.
@ast
Kinetics of onset of rate-depe ...... s for their subclassification.
@en
Kinetics of onset of rate-depe ...... s for their subclassification.
@nl
type
label
Kinetics of onset of rate-depe ...... s for their subclassification.
@ast
Kinetics of onset of rate-depe ...... s for their subclassification.
@en
Kinetics of onset of rate-depe ...... s for their subclassification.
@nl
prefLabel
Kinetics of onset of rate-depe ...... s for their subclassification.
@ast
Kinetics of onset of rate-depe ...... s for their subclassification.
@en
Kinetics of onset of rate-depe ...... s for their subclassification.
@nl
P356
P1476
Kinetics of onset of rate-depe ...... s for their subclassification.
@en
P2093
Campbell TJ
P304
P356
10.1093/CVR/17.6.344
P577
1983-06-01T00:00:00Z