CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis - Wikidata - awgldk - TriplyDB

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

http://www.wikidata.org/entity/Q34937677

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The 20th anniversary of interleukin-2 therapy: bimodal role explaining longstanding random induction of complete clinical responses Tregs in infection and vaccinology: heroes or traitors?The role of integrins in TGFβ activation in the tumour stroma Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells.Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation.HCV adaptations to altered CD8(+) T-cell immunity during pregnancy Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.Cis-acting pathways selectively enforce the non-immunogenicity of shed placental antigen for maternal CD8 T cells.Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.Therapeutic regulatory T cells subvert effector T cell function in inflamed islets to halt autoimmune diabetes.Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone marrow and spinal cord while preserving peripheral regulatory mechanisms.Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.T cell exhaustion during persistent viral infections.Influence of sex hormones and genetic predisposition in Sjögren's syndrome: a new clue to the immunopathogenesis of dry eye disease T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens Foxp3+ Regulatory T-cells and IL-2: The Moirai of T-cell Fates?Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus.The multifaceted role of CD4(+) T cells in CD8(+) T cell memory High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.CD4+ T helper cells use CD154-CD40 interactions to counteract T reg cell-mediated suppression of CD8+ T cell responses to influenza.IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection Cytokines in cancer immunotherapy.Reference Values for a Panel of Cytokinergic and Regulatory Lymphocyte Subpopulations.Attenuation of donor-reactive T cells allows effective control of allograft rejection using regulatory T cell therapy.T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses.Regulatory T cells in systemic lupus erythematosus.Tumor Microenvironment as a New Target for Tumor Immunotherapy of Polysaccharides.Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance.Lymph node - an organ for T-cell activation and pathogen defense.Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis.Association of Mutations in Toll-like Receptor 2 Signaling Genes With Fulminant Form of Hepatitis B-Related Acute Liver Failure.Chimerism-based tolerance in organ transplantation: preclinical and clinical studies.FoxP3⁺ regulatory CD4 T cells control the generation of functional CD8 memory.Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses.Interleukin-2 treatment reverses effects of cAMP-responsive element modulator α-over-expressing T cells in autoimmune-prone mice.Opposing effects of androgen ablation on immune function in prostate cancer.

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CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

http://www.wikidata.org/entity/Q34937677

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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type

label

CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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prefLabel

CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

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PNAS.1103782108

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Proceedings of the National Academy of Sciences of the United States of America

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CD4+CD25+ regulatory T cells c ...... by modulating IL-2 homeostasis

@en

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Alice McNally

http://www.w3.org/2001/XMLSchema#string

Geoffrey R Hill

http://www.w3.org/2001/XMLSchema#string

Ranjeny Thomas

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Raymond J Steptoe

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Tim Sparwasser

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P2860

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

How regulatory T cells work

T cell receptor antagonist peptides induce positive selection

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice.

FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells.

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo.

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7529-7534

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scholarly article

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10.1073/PNAS.1103782108

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18

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108

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51060271

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21502514

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3088596

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