The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications.
about
Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elementsRole of CTCF protein in regulating FMR1 locus transcriptionThe long-range interaction landscape of gene promotersPcG proteins, DNA methylation, and gene repression by chromatin looping.Evidence for RNA-mediated toxicity in the fragile X-associated tremor/ataxia syndrome.Integrating one-dimensional and three-dimensional maps of genomes.Examination of FMR1 transcript and protein levels among 74 premutation carriers.Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR geneThe distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome.Analysis of long-range chromatin interactions using Chromosome Conformation Capture.A chromatin insulator driving three-dimensional Polycomb response element (PRE) contacts and Polycomb association with the chromatin fiber.The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules.Histones: at the crossroads of peptide and protein chemistry.Modulated contact frequencies at gene-rich loci support a statistical helix model for mammalian chromatin organizationUsing DNA methylation to understand biological consequences of genetic variability.Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-CX-linked mental retardation and epigenetics.GC- and AT-rich chromatin domains differ in conformation and histone modification status and are differentially modulated by Rpd3pAnalysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elementsConserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia.Variable requirements for DNA-binding proteins at polycomb-dependent repressive regions in human HOX clusters.Long-range chromosomal interactions and gene regulationYeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions.Closely linked cis-acting modifier of expansion of the CGG repeat in high risk FMR1 haplotypes.Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C).Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.Human pluripotent stem cell models of Fragile X syndrome.Characterization of chromosomal architecture in Arabidopsis by chromosome conformation capture.Mapping in vivo chromatin interactions in yeast suggests an extended chromatin fiber with regional variation in compaction.Recovering ensembles of chromatin conformations from contact probabilities.
P2860
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P2860
The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The active FMR1 promoter is as ...... d local histone modifications.
@ast
The active FMR1 promoter is as ...... d local histone modifications.
@en
type
label
The active FMR1 promoter is as ...... d local histone modifications.
@ast
The active FMR1 promoter is as ...... d local histone modifications.
@en
prefLabel
The active FMR1 promoter is as ...... d local histone modifications.
@ast
The active FMR1 promoter is as ...... d local histone modifications.
@en
P2093
P2860
P356
P1476
The active FMR1 promoter is as ...... d local histone modifications.
@en
P2093
Job Dekker
Nele Gheldof
Tomoko M Tabuchi
P2860
P304
12463-12468
P356
10.1073/PNAS.0605343103
P407
P577
2006-08-04T00:00:00Z