AAV-mediated photoreceptor transduction of the pig cone-enriched retina. - Wikidata - awgldk - TriplyDB

AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

http://www.wikidata.org/entity/Q35092093

about

MicroRNA-restricted transgene expression in the retina The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy.Myosin7a deficiency results in reduced retinal activity which is improved by gene therapy.Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection.Gene augmentation for adRP mutations in RHO.Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease.Vector platforms for gene therapy of inherited retinopathies.AAV9 targets cone photoreceptors in the nonhuman primate retina.Recombinant vectors based on porcine adeno-associated viral serotypes transduce the murine and pig retina Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient.Gene Therapy of ABCA4-Associated Diseases.Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials.Gene therapy of inherited retinopathies: a long and successful road from viral vectors to patients.Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.Rhodopsin targeted transcriptional silencing by DNA-binding.A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa The gene therapy revolution in ophthalmology.Combined rod and cone transduction by adeno-associated virus 2/8.Effective delivery of large genes to the retina by dual AAV vectors.Novel adeno-associated viral vectors for retinal gene therapy.Gene therapy in animal models of autosomal dominant retinitis pigmentosa Animal modelling for inherited central vision loss.Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization model Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward.A novel formulation based on 2,3-di(tetradecyloxy)propan-1-amine cationic lipid combined with polysorbate 80 for efficient gene delivery to the retina.Leber's congenital amaurosis and the role of gene therapy in congenital retinal disorders Retinal transduction profiles by high-capacity viral vectors.Efficient gene delivery to the cone-enriched pig retina by dual AAV vectors.A novel nonviral gene delivery system for treating Leber's congenital amaurosis.Design and Development of AAV-based Gene Supplementation Therapies for Achromatopsia and Retinitis Pigmentosa.Dual AAV Vectors for Stargardt Disease.Triple Vectors Expand AAV Transfer Capacity in the Retina.ASSESSMENT OF AAV SEROTYPE TROPISM IN HUMAN RETINAL EXPLANTS.High-throughput screening identifies kinase inhibitors that increase dual AAV vectors transduction <i>in vitro</i> and in mouse retina.Behavioral Assessment of Vision in Pigs

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P2860

AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

http://www.wikidata.org/entity/Q35092093

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

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AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

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AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

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AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

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P2860

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Vision 1 year after gene therapy for Leber's congenital amaurosis

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year

Effect of gene therapy on visual function in Leber's congenital amaurosis

Restoration of cone vision in a mouse model of achromatopsia

Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column.

Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations

Molecular genetics of Leber congenital amaurosis.

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Francesca Simonelli

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Edoardo Villani

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