Initial efforts toward the optimization of arylomycins for antibiotic activity.
about
Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulenceA new antibacterial lipopeptide found by UPLC-MS from an actinomycete Streptomyces sp. HCCB10043.A putative cro-like repressor contributes to arylomycin resistance in Staphylococcus aureus.Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidaseType I signal peptidase and protein secretion in Staphylococcus aureus.An Alternative Terminal Step of the General Secretory Pathway in Staphylococcus aureus.Membrane proteases in the bacterial protein secretion and quality control pathway.The inhibition of type I bacterial signal peptidase: Biological consequences and therapeutic potential.Mechanism of action of the arylomycin antibiotics and effects of signal peptidase I inhibitionEfforts toward broadening the spectrum of arylomycin antibiotic activity.Signal peptidase I: cleaving the way to mature proteins.Bacterial type I signal peptidases as antibiotic targets.Strained cyclophane natural products: macrocyclization at its limits.Prospects for new antibiotics: a molecule-centered perspective.Bacterial proteases, untapped antimicrobial drug targets.Activity of the type I signal peptidase inhibitor MD3 against multidrug-resistant Gram-negative bacteria alone and in combination with colistin.Polishing the tarnished silver bullet: the quest for new antibiotics.Harnessing the power of transposon mutagenesis for antibacterial target identification and evaluation.Recent advances in synthetic lipopeptides as anti-microbial agents: designs and synthetic approaches.Scalable Access to Arylomycins via C-H Functionalization Logic.Optimization of a β-Lactam Scaffold for Antibacterial Activity via the Inhibition of Bacterial Type I Signal Peptidase.
P2860
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P2860
Initial efforts toward the optimization of arylomycins for antibiotic activity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@ast
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@en
type
label
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@ast
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@en
prefLabel
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@ast
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@en
P2093
P2860
P356
P1476
Initial efforts toward the optimization of arylomycins for antibiotic activity.
@en
P2093
Floyd E Romesberg
Mark A Schallenberger
Peter A Smith
P2860
P304
P356
10.1021/JM1016126
P407
P577
2011-06-28T00:00:00Z