Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide
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Targeting Antibiotic ResistanceEndless Resistance. Endless Antibiotics?In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.Peripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics.Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]-Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE.Total Synthesis and Structural Reassignment of Aspergillomarasmine A.Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.Developments in Glycopeptide Antibiotics.Natural Products as Platforms To Overcome Antibiotic Resistance.Remodeling vancomycin yields a victory in the battle against bacteria.Novel Modifications of Glycopeptide Antibiotics via Total Synthesis.The race for antimicrobials in the multidrug resistance era.
P2860
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P2860
Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Total syntheses and initial ev ...... fications for the glycopeptide
@ast
Total syntheses and initial ev ...... fications for the glycopeptide
@en
type
label
Total syntheses and initial ev ...... fications for the glycopeptide
@ast
Total syntheses and initial ev ...... fications for the glycopeptide
@en
prefLabel
Total syntheses and initial ev ...... fications for the glycopeptide
@ast
Total syntheses and initial ev ...... fications for the glycopeptide
@en
P2093
P2860
P356
P1476
Total syntheses and initial ev ...... fications for the glycopeptide
@en
P2093
Akinori Okano
Alex W Schammel
Atsushi Nakayama
Dale L Boger
Erick A Lindsey
Karen C Collins
Yiqing Feng
P2860
P304
P356
10.1021/JACS.5B01008
P407
P577
2015-03-09T00:00:00Z