Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
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The internal thioester and the covalent binding properties of the complement proteins C3 and C4Binding of platelet-derived growth factor-BB and transforming growth factor-beta 1 to alpha 2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized alpha 2-macroglobulin conformations.Differences in the binding of transforming growth factor beta 1 to the acute-phase reactant and constitutively synthesized alpha-macroglobulins of rat.Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin.Chemical modification of alpha2-macroglobulin to generate derivatives that bind transforming growth factor-beta with increased affinity.Low resolution X-ray structure of human methylamine-treated alpha 2-macroglobulin.Effect of methylamine and plasmin on the conformation of human alpha 2-macroglobulin as revealed by differential scanning calorimetric analysisDestruction of articular cartilage by alpha 2 macroglobulin elastase complexes: role in rheumatoid arthritis.Guinea pig macroalbumin. A major inhibitor of activated Hageman factor in plasma with an alpha 2-macroglobulin-like natureThird component of human complement: localization of the internal thiolester bond.Characterization of the Mr difference between secreted murine fourth component of complement and the major plasma form: evidence for carboxyl-terminal cleavage of the alpha chain.Sequence determination of the thiolester site of the fourth component of human complement.Contribution of plasma protease inhibitors to the inactivation of kallikrein in plasma.Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4.Invertebrate alpha 2-macroglobulin: structure-function and the ancient thiol ester bond.Significance of the regulation of plasma kallikrein by alpha 2M.Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris.Evidence for similar conformational changes in alpha 2-macroglobulin on reaction with primary amines or proteolytic enzymes.The role of enzyme lysyl amino groups in the reaction with alpha 2-macroglobulin.Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeiaThe structure around the thioester bond in bovine alpha 2-macroglobulin. Possible implications for the conformational stability of the inhibitor on thioester cleavage.Functional modifications of alpha 2-macroglobulin by primary amines. Kinetics of inactivation of alpha 2-macroglobulin by methylamine, and formation of anomalous complexes with trypsin.Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin.Purification and characterization of an alpha 2-macroglobulin-like proteinase inhibitor from plasma of the crayfish Pacifastacus leniusculus.The conformational changes of alpha 2-macroglobulin induced by methylamine or trypsin. Characterization by extrinsic and intrinsic spectroscopic probes.Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond.Mouse alpha-macroglobulin. Structure, function and a molecular model.Binding of proteinases to human alpha 2-macroglobulin with its thioester bonds cleaved by methylamine in the presence of a thiol-group-cyanylating reagent.Differential scanning calorimetry of alpha 2-macroglobulin and alpha 2-macroglobulin-proteinase complexes.Non-enzymic activation of the covalent binding reaction of the complement protein C3.Identification of the high affinity binding site in transforming growth factor-beta involved in complex formation with alpha 2-macroglobulin. Implications regarding the molecular mechanisms of complex formation between alpha 2-macroglobulin and growSite-specific cleavage--a model system for the identification of lipid-modified glutamate residues in proteins.Rat plasma alpha 1-inhibitor3: a member of the alpha-macroglobulin family.The properties of rabbit alpha1-macroglobulin upon activation are distinct from those of rabbit and human alpha2-macroglobulins.
P2860
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P2860
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
description
1981 nî lūn-bûn
@nan
1981 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@ast
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@en
type
label
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@ast
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@en
prefLabel
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@ast
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@en
P2860
P356
P1476
Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester.
@en
P2093
J B Howard
P2860
P304
P356
10.1073/PNAS.78.4.2235
P407
P577
1981-04-01T00:00:00Z