The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.
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Janus Compounds, 5-Chloro-N⁴-methyl-N⁴-aryl-9H-pyrimido[4,5-b]indole-2,4-diamines, Cause Both Microtubule Depolymerizing and Stabilizing Effects.Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2.Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents.Antiangiogenesis and vascular disrupting agents in cancer: circumventing resistance and augmenting their therapeutic utility.Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
P2860
The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The design, synthesis and biol ...... as potential antitumor agents.
@ast
The design, synthesis and biol ...... as potential antitumor agents.
@en
type
label
The design, synthesis and biol ...... as potential antitumor agents.
@ast
The design, synthesis and biol ...... as potential antitumor agents.
@en
prefLabel
The design, synthesis and biol ...... as potential antitumor agents.
@ast
The design, synthesis and biol ...... as potential antitumor agents.
@en
P2093
P2860
P1476
The design, synthesis and biol ...... as potential antitumor agents
@en
P2093
Aleem Gangjee
Anja Bastian
Cynthia Zammiello
Ernest Hamel
Michael Ihnat
Susan L Mooberry
P2860
P304
P356
10.1016/J.BMC.2015.03.061
P407
P577
2015-03-30T00:00:00Z