Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.
about
Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicksHMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme AThrombin and vascular inflammationRole of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated tracheaRNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammationPerforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis.Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.Review article: proteinase-activated receptors - novel signals for gastrointestinal pathophysiology.The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.Granzyme A activates another way to dieGranzymes in age-related cardiovascular and pulmonary diseases.Protease activated receptors: theme and variations.Interactions of mast cell tryptase with thrombin receptors and PAR-2.Death by a thousand cuts: granzyme pathways of programmed cell deathProtease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: thrombin as signaling molecule in the brain.Non-apoptotic functions of granzymes.Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.Expression of multiple granzymes by cytotoxic T lymphocyte implies that they activate diverse apoptotic pathways in target cells.Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor.The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression.Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4.N-linked glycosylation regulates human proteinase-activated receptor-1 cell surface expression and disarming via neutrophil proteinases and thermolysin.Granzyme A and thrombin differentially promote the release of interleukin-8 from alveolar epithelial A549 cells.Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.Expression of granzyme A in human polymorphonuclear neutrophils.Granzymes, cytotoxic granules and cell death: the early work of Dr. Jurg Tschopp.Thrombin and its receptor in growth control.Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma.Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes.The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin.Cleavage of the thrombin receptor: identification of potential activators and inactivators.Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro.
P2860
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P2860
Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@ast
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@en
type
label
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@ast
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@en
prefLabel
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@ast
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@en
P2093
P2860
P356
P1476
Granzyme A released upon stimu ...... neuronal cells and astrocytes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.17.8112
P407
P50
P577
1994-08-01T00:00:00Z