Targets and mechanisms for the regulation of translation in malignant transformation.
about
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancerMining expressed sequence tags identifies cancer markers of clinical interestTracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4EFibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysHypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsPCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexesThe eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral InfectionsProtein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cellsDeletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow miceThe Role of Retinoic Acid (RA) in Spermatogonial DifferentiationData mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction.Enhancing mTOR-targeted cancer therapy.17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response.Targeting the translational machinery as a novel treatment strategy for hematologic malignancieshnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation.eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.Generalized portrait of cancer metabolic pathways inferred from a list of genes overexpressed in cancerProtein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells.Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis.Metabolic alterations and targeted therapies in prostate cancer.FASN and CD36 predict survival in rituximab-treated diffuse large B-cell lymphoma.Lowly expressed ribosomal protein s19 in the feces of patients with colorectal cancer.Faecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer.Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis.Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective.Initiation factor modifications in the preapoptotic phase.The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck.PKCδ Regulates Translation Initiation through PKR and eIF2α in Response to Retinoic Acid in Acute Myeloid Leukemia CellsOpposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancyVesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation.RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.Tumorigenic activity and therapeutic inhibition of Rheb GTPase.Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application.Differential regulation of oestrogen receptor β isoforms by 5' untranslated regions in cancerThe adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.
P2860
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P2860
Targets and mechanisms for the regulation of translation in malignant transformation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Targets and mechanisms for the regulation of translation in malignant transformation.
@ast
Targets and mechanisms for the regulation of translation in malignant transformation.
@en
type
label
Targets and mechanisms for the regulation of translation in malignant transformation.
@ast
Targets and mechanisms for the regulation of translation in malignant transformation.
@en
prefLabel
Targets and mechanisms for the regulation of translation in malignant transformation.
@ast
Targets and mechanisms for the regulation of translation in malignant transformation.
@en
P2860
P356
P1433
P1476
Targets and mechanisms for the regulation of translation in malignant transformation.
@en
P2093
Michael J Clemens
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207544
P407
P577
2004-04-01T00:00:00Z
P5875
P6179
1051106413