Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion.
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Mechanisms of action of glucagon-like peptide 1 in the pancreasRestructuring of pancreatic islets and insulin secretion in a postnatal critical window.CaV2.3 channel and PKClambda: new players in insulin secretionCell Cycle-Dependent Localization of Voltage-Dependent Calcium Channels and the Mitotic Apparatus in a Neuroendocrine Cell Line(AtT-20).Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunctionRegulation of insulin secretion: role of mitochondrial signalling.Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volumeCharacterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.Evolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins.Metabolome response to glucose in the β-cell line INS-1 832/13.Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta-cells by kinetic modeling of granule exocytosis.Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesionRegulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.Granule mobility, fusion frequency and insulin secretion are differentially affected by insulinotropic stimuli.Noradrenaline inhibits exocytosis via the G protein βγ subunit and refilling of the readily releasable granule pool via the α(i1/2) subunit.The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approachInsulinotropic effect of high potassium concentration beyond plasma membrane depolarization.Plasma membrane depolarization as a determinant of the first phase of insulin secretion.Metabolic amplifying pathway increases both phases of insulin secretion independently of beta-cell actin microfilaments.Extracellular ATP and zinc are co-secreted with insulin and activate multiple P2X purinergic receptor channels expressed by islet beta-cells to potentiate insulin secretion.Insulin secretion in the conscious mouse is biphasic and pulsatile.Bidirectional insulin granule turnover in the submembrane space during K(+) depolarization-induced secretion.Impact of a mild decrease in fasting plasma glucose on β-cell function in healthy subjects and patients with type 2 diabetes.Analysis of glucose metabolism in cynomolgus monkeys during aging.Insulin granule trafficking in beta-cells: mathematical model of glucose-induced insulin secretion.Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubules.Disruption and stabilization of β-cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store-operated Ca2+ entry.Dynamics of glucose-induced insulin secretion in normal human islets.Bis-Pyrano Prenyl Isoflavone Improves Glucose Homeostasis by Inhibiting Dipeptidyl Peptidase-4 in Hyperglycemic Rats.Annexin I stimulates insulin secretion through regulation of cytoskeleton and PKC activity
P2860
Q24683764-A0A3E0BB-07A9-4A10-9859-268F42D26C79Q33267293-B8C93396-B0F1-4A87-8AF5-E1605EBECA21Q33566046-B03AA2CB-A0F0-4776-9E3C-84FF83F99A24Q33622151-68ACF581-954C-4D21-ADCC-3A6A342F3F29Q33751570-53FD6E2C-CA7E-4F77-BBF7-66F45D261B28Q33914248-F6EDBE86-9181-4EAE-97AE-555E4CCE0578Q34628129-4C9A06D6-3605-4DDF-BF10-3255942E3221Q34776309-984F00D2-608C-4FFE-A3E3-806BF5AB6660Q35536327-8359B450-23B3-4A3D-BF2E-5ECF01FA5006Q36041923-525EDDCB-E9A4-4D59-8510-0B9FF6DD340CQ36760453-30E7D87F-881D-41C0-95A2-7203ECB6678CQ36838909-9B5B789B-9A00-4E50-990D-9965140908CAQ36990871-86FF32FF-E67D-4872-91AD-EBBA3DD439EEQ37603286-4607E9A6-5FB2-4CA6-BEFC-22A3F2F7AA1CQ38917136-10C89BCC-4777-4FC0-82ED-0AA35C3FC87CQ39678366-AEDCA25A-6B2B-409C-B35A-13F5A556F9A8Q41356232-1E4FA75E-57A0-408F-A23E-740BDAC5A6B9Q42452912-DCF4597D-621D-40F2-A603-5E724949E634Q42454344-B6CAAB6D-80E6-43B1-B7E7-90AA4E09C500Q43059442-A586966A-EAEC-4349-8E21-EB0561CDA70EQ43242952-B83D45F8-F3FC-498B-8EE0-309E84C4C6DFQ44914595-30EB827C-443C-4ECC-87F7-EE9BD8638203Q50518753-B80AD2A5-BC6B-472B-A1EE-2C8C5864F552Q50668568-8A4D0FBA-215C-4EBB-A3E7-295174FF2EE5Q51365765-5EDF2CC0-3E90-46A9-A5BB-3C5F3D3EA2C5Q51916491-DEEBD082-987D-4BB7-AC9C-032351AD8EA8Q52606205-D8716047-D1F2-48FE-AC37-19C45ADD8DE8Q52619261-8C876D48-1FCE-44B9-9996-A90844DB3428Q53387949-64D0BCD5-AFBC-454E-B58F-1A870B620E3DQ55021942-1249CB0E-540B-43B9-8A1A-D1EAC81A9196Q58282677-4941D90B-860A-4D02-A911-7B7F7559FEBB
P2860
Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@ast
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@en
type
label
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@ast
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@en
prefLabel
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@ast
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@en
P2860
P1476
Hypothesis: one rate-limiting ...... -stimulated insulin secretion.
@en
P2093
Geoffrey W G Sharp
Susanne G Straub
P2860
P304
P356
10.1152/AJPCELL.00079.2004
P577
2004-09-01T00:00:00Z