Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells - Wikidata - awgldk - TriplyDB

Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells

Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells

http://www.wikidata.org/entity/Q35892477

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Aging of hematopoietic stem cells: DNA damage and mutations?Uncovering the role of p53 splice variants in human malignancy: a clinical perspective Transcriptional regulation by coactivators in embryonic stem cells Systematic identification of gene family regulators in mouse and human embryonic stem cells p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model Redox homeostasis: the linchpin in stem cell self-renewal and differentiation Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression Akt3 is responsible for the survival and proliferation of embryonic stem cells Large-scale quality analysis of published ChIP-seq data.Gene expression variability in mammalian embryonic stem cells using single cell RNA-seq data Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas.cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex p53 binding to human genome: crowd control navigation in chromatin context Detained introns are a novel, widespread class of post-transcriptionally spliced introns.TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasion Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.CARM1 regulates astroglial lineage through transcriptional regulation of Nanog and posttranscriptional regulation by miR92a.Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity An acetyl-methyl switch drives a conformational change in p53.Oncogenesis and induced pluripotency - commonalities of signalling pathways Chromatin landscapes of retroviral and transposon integration profiles Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53 p53 loss increases the osteogenic differentiation of bone marrow stromal cells An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells.Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses p53 and rapamycin are additive.Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells

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Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells

http://www.wikidata.org/entity/Q35892477

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

@yue

2012年論文

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2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Distinct regulatory mechanisms ...... genes in embryonic stem cells

@ast

Distinct regulatory mechanisms ...... genes in embryonic stem cells

@en

type

label

Distinct regulatory mechanisms ...... genes in embryonic stem cells

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Distinct regulatory mechanisms ...... genes in embryonic stem cells

@en

prefLabel

Distinct regulatory mechanisms ...... genes in embryonic stem cells

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Distinct regulatory mechanisms ...... genes in embryonic stem cells

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Distinct regulatory mechanisms ...... genes in embryonic stem cells

@en

P2093

Jianxin Shi

http://www.w3.org/2001/XMLSchema#string

Jing Huang

http://www.w3.org/2001/XMLSchema#string

Mangmang Li

http://www.w3.org/2001/XMLSchema#string

Wendy Dubois

http://www.w3.org/2001/XMLSchema#string

Xiaolin Wu

http://www.w3.org/2001/XMLSchema#string

Yunlong He

http://www.w3.org/2001/XMLSchema#string

P2860

Model-based analysis of ChIP-Seq (MACS)

p53 is regulated by the lysine demethylase LSD1

Repression of p53 activity by Smyd2-mediated methylation

Modulation of p53 function by SET8-mediated methylation at lysine 382

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Histone H3K27ac separates active from poised enhancers and predicts developmental state

c-Myc regulates transcriptional pause release

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Mediator and cohesin connect gene expression and chromatin architecture

Induced pluripotent stem cell lines derived from human somatic cells

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30-42

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1

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