Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells
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Aging of hematopoietic stem cells: DNA damage and mutations?Uncovering the role of p53 splice variants in human malignancy: a clinical perspectiveTranscriptional regulation by coactivators in embryonic stem cellsSystematic identification of gene family regulators in mouse and human embryonic stem cellsp53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressAn African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse modelRedox homeostasis: the linchpin in stem cell self-renewal and differentiationNotchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cellsA RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer CellsForced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expressionAkt3 is responsible for the survival and proliferation of embryonic stem cellsLarge-scale quality analysis of published ChIP-seq data.Gene expression variability in mammalian embryonic stem cells using single cell RNA-seq dataGlobal analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas.cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic OsteosarcomaPint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complexp53 binding to human genome: crowd control navigation in chromatin contextDetained introns are a novel, widespread class of post-transcriptionally spliced introns.TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasionInteractions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.CARM1 regulates astroglial lineage through transcriptional regulation of Nanog and posttranscriptional regulation by miR92a.Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activityAn acetyl-methyl switch drives a conformational change in p53.Oncogenesis and induced pluripotency - commonalities of signalling pathwaysChromatin landscapes of retroviral and transposon integration profilesTranscriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53p53 loss increases the osteogenic differentiation of bone marrow stromal cellsAn Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells.Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damageMutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analysesp53 and rapamycin are additive.Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic StabilityRibosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells
P2860
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P2860
Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@ast
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@en
type
label
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@ast
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@en
prefLabel
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@ast
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@en
P2093
P2860
P1433
P1476
Distinct regulatory mechanisms ...... genes in embryonic stem cells
@en
P2093
Jianxin Shi
Jing Huang
Mangmang Li
Wendy Dubois
Xiaolin Wu
Yunlong He
P2860
P356
10.1016/J.MOLCEL.2012.01.020
P577
2012-03-01T00:00:00Z