Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice. - Wikidata - awgldk - TriplyDB

Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.

Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.

http://www.wikidata.org/entity/Q35919383

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Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration Advances in carcinogenic metal toxicity and potential molecular markers Age related shift in the mutation spectra of germline and somatic NF2 mutations: hypothetical role of DNA repair mechanisms.Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury.DNA repair deficiency in neurodegeneration.Cellular stress response pathways and ageing: intricate molecular relationships DNA end joining becomes less efficient and more error-prone during cellular senescence.BAX and tumor suppressor TRP53 are important in regulating mutagenesis in spermatogenic cells in mice.SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner Tissue-specific differences in the accumulation of sequence rearrangements with age.A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation.Higher expression of somatic repair genes in long-lived ant queens than workers Changes in DNA repair during aging.Mechanistic insight into DNA damage and repair in ischemic stroke: exploiting the base excision repair pathway as a model of neuroprotection.Metabolism, genomics, and DNA repair in the mouse aging liver.DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.Aging results in differential regulation of DNA repair pathways in pachytene spermatocytes in the Brown Norway rat Activities of DNA base excision repair enzymes in liver and brain correlate with body mass, but not lifespan.Base excision repair in physiology and pathology of the central nervous system Base excision repair, aging and health span.Photoprotection in human skin--a multifaceted SOS response.Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice Base excision repair in the mammalian brain: implication for age related neurodegeneration Spontaneous mutagenesis is enhanced in Apex heterozygous mice.DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae.Ageing of the male germ line.The impact of base excision DNA repair in age-related neurodegenerative diseases The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice.Transcriptional profiling of the age-related response to genotoxic stress points to differential DNA damage response with age.Microsatellite instability in Arabidopsis increases with plant development.Reduced DNA gap repair in aging rat neuronal extracts and its restoration by DNA polymerase beta and DNA-ligase.Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage.A reduction in DNA damage in neural tissue and peripheral blood of old mice treated with caffeine.Aging related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury.

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P2860

Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.

http://www.wikidata.org/entity/Q35919383

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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2002年论文

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2002年论文

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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Mutation Research

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Attenuation of DNA polymerase ...... ced mutagenicity in aged mice.

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P2093

Ahmad R Heydari

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Cirlette Ganir

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Diane C Cabelof

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Julian J Raffoul

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Sunitha Yanamadala

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ZhongMao Guo

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P2860

Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

Mutation frequency and specificity with age in liver, bladder and brain of lacI transgenic mice

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

DNA polymerases delta and epsilon in developing and aging rat brain

Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.

Significance of multiple mutations in cancer.

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10.1016/S0027-5107(02)00003-9

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3339152

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