Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR.
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Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56N(6)-methyladenosine Modulates Messenger RNA Translation EfficiencyRNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usageThe ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translationAdaptive and maladaptive expression of the mRNA regulatory protein HuRThe proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein UMultiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosisThe hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvationMembers of a large retroposon family are determinants of post-transcriptional gene expression in LeishmaniaElevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells.Renal response to metabolic acidosis: role of mRNA stabilization.Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus.Transcriptional control of human antigen R by bone morphogenetic proteinAmino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathwayExpression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cellsPromotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family membersRNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expressionMechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation.Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma.Regulation of xCT expression and system x (c) (-) function in neuronal cells.HuR stabilizes vacuolar H+-translocating ATPase mRNA during cellular energy depletionDerepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cellsL-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression.MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.Amino acid transporters: roles in amino acid sensing and signalling in animal cells.Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway.Role of AUF1 and HuR in the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK₁-F⁺ cellsGlobal mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response.A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translationThe RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cellsExpression and distribution of HuR during ATP depletion and recovery in proximal tubule cellsChronic ethanol exposure increases the binding of HuR to the TNFalpha 3'-untranslated region in macrophagesNutritional control of gene expression: how mammalian cells respond to amino acid limitation.HuR inhibits apoptosis by amplifying Akt signaling through a positive feedback loop.Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin.Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cellsATF4-dependent transcription mediates signaling of amino acid limitation.Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.
P2860
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P2860
Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@ast
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@en
type
label
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@ast
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@en
prefLabel
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@ast
Nutritional control of mRNA st ...... plasmic shuttling protein HuR.
@en
P2093
P2860
P356
P1476
Nutritional control of mRNA st ...... oplasmic shuttling protein HuR
@en
P2093
Bedabrata Sarkar
James Fernandez
Laura E Nagy
Maria Hatzoglou
Martin D Snider
Robert J Schneider
P2860
P304
41539-41546
P356
10.1074/JBC.M204850200
P407
P577
2002-08-23T00:00:00Z