Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.
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Positive and negative functions of B lymphocytes in tumorsCrystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activityCancers Related to Immunodeficiencies: Update and PerspectivesThe Multifaceted Roles Neutrophils Play in the Tumor MicroenvironmentB cells and the humoral response in melanoma: The overlooked players of the tumor microenvironmentBig opportunities for small molecules in immuno-oncology.Growth and metastasis of B16-F10 melanoma cells is not critically dependent on host CD73 expression in mice.Anti-CD73 in cancer immunotherapy: awakening new opportunities.Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cellsAdenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escapeTargeting CD73 in the tumor microenvironment with MEDI9447.Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma.High expression of ecto-nucleotidases CD39 and CD73 in human endometrial tumors.Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma modelTargeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer.Regulatory B cells in anti-tumor immunity.CD73-adenosine: a next-generation target in immuno-oncology.Downregulation of CD73 in 4T1 breast cancer cells through siRNA-loaded chitosan-lactate nanoparticles.A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation.Pro- and anti-tumour effects of B cells and antibodies in cancer: a comparison of clinical studies and preclinical models.The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.The role of pro-inflammatory cytokines and immune cells in colorectal carcinoma progression.The adenosinergic system in cancer: Key therapeutic target.Multifaceted Effects of Extracellular Adenosine Triphosphate and Adenosine in the Tumor-Host Interaction and Therapeutic Perspectives.Functional Conversion and Dominance of γδ T Subset in Mouse Experimental Autoimmune Uveitis.New Insights into the Immunobiology of Mononuclear Phagocytic Cells and Their Relevance to the Pathogenesis of Cardiovascular Diseases.Exomechip Analyses Identify Genes Affecting Mortality after HLA-Matched Unrelated Donor Blood and Marrow Transplantation.Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer.CD73 expression and clinical significance in human metastatic melanoma.
P2860
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P2860
Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@ast
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@en
type
label
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@ast
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@en
prefLabel
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@ast
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@en
P2093
P2860
P356
P1476
Inhibition of CD73 improves B ...... in a mouse model of melanoma.
@en
P2093
Aldo Pinto
Antonella Montinaro
Antonio Luciano
Carla Cicala
Claudio Arra
Giovanni Forte
Ian M Adcock
Piera Maiolino
Rosalinda Sorrentino
Silvana Morello
P2860
P304
P356
10.4049/JIMMUNOL.1200744
P407
P577
2012-07-23T00:00:00Z