Specificity requirements for human telomere protein interaction with telomerase holoenzyme
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Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1Finding the end: recruitment of telomerase to telomeresShort telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancyMultiple facets of TPP1 in telomere maintenanceProgress in structural studies of telomeraseStructure of Est3 reveals a bimodal surface with differential roles in telomere replicationTelomerase Regulation from Beginning to the EndThe shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulationModern genome editing meets telomeres: the many functions of TPP1The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityInhibition of telomerase recruitment and cancer cell deathIdentification of human TERT elements necessary for telomerase recruitment to telomeres.Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.Human telomerase: biogenesis, trafficking, recruitment, and activation.Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancerThe telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3' end availability.Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactionsTpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1.Essential role for the TRF2 telomere protein in adult skin homeostasisTelomerase activation after recruitment in fission yeast.The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cellsA mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.Shelterin Protects Chromosome Ends by Compacting Telomeric ChromatinPOT1-TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism.NEK6-mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment.Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres.Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance.Control of telomerase action at human telomeresCorrelation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancerPhosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitmentThe shelterin complex and hematopoiesis.Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces.Structural and functional consequences of a disease mutation in the telomere protein TPP1.Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.Cdc13 at a crossroads of telomerase action
P2860
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P2860
Specificity requirements for human telomere protein interaction with telomerase holoenzyme
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Specificity requirements for h ...... ion with telomerase holoenzyme
@ast
Specificity requirements for h ...... ion with telomerase holoenzyme
@en
type
label
Specificity requirements for h ...... ion with telomerase holoenzyme
@ast
Specificity requirements for h ...... ion with telomerase holoenzyme
@en
prefLabel
Specificity requirements for h ...... ion with telomerase holoenzyme
@ast
Specificity requirements for h ...... ion with telomerase holoenzyme
@en
P2093
P2860
P356
P1476
Specificity requirements for h ...... ion with telomerase holoenzyme
@en
P2093
Alec N Sexton
Daniel T Youmans
Kathleen Collins
P2860
P304
34455-34464
P356
10.1074/JBC.M112.394767
P407
P577
2012-08-14T00:00:00Z