Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function.
about
Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomasInstability of succinate dehydrogenase in SDHD polymorphism connects reactive oxygen species production to nuclear and mitochondrial genomic mutations in yeastHigh-throughput screening for the identification of new therapeutic options for metastatic pheochromocytoma and paragangliomaSuccinate-to-fumarate ratio as a new metabolic marker to detect the presence of SDHB/D-related paraganglioma: initial experimental and ex vivo findings.Current views on cell metabolism in SDHx-related pheochromocytoma and paragangliomaCurrent approaches and recent developments in the management of head and neck paragangliomas.Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatmentIntrinsically disordered segments affect protein half-life in the cell and during evolution.Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradationGenetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment optionsHistone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperonesHypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction.Pheochromocytoma: Gasping for Air.Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation.Altered expression of Tumor Necrosis Factor Alpha -Induced Protein 3 correlates with disease severity in Ulcerative ColitisBortezomib Alone and in Combination With Salinosporamid A Induces Apoptosis and Promotes Pheochromocytoma Cell Death In Vitro and in Female Nude Mice.Pheochromocytoma: The First Metabolic Endocrine Cancer.Blocking protein quality control to counter hereditary cancers.Implications of SDHB genetic testing in patients with sporadic pheochromocytoma.
P2860
Q24597432-346A6A99-0676-44E6-86E9-D57918D1C815Q27938745-1C00B33C-0167-4E62-BEF4-2606C596469BQ28541862-3A538916-6103-42AF-9EB9-7EE967B67726Q33585065-3ECD04D7-4D71-4A22-8016-E56D543091AAQ33590969-9514772E-A2CB-4DC1-B57D-505888214FB4Q34204524-36CAD3BF-5142-48B5-BCDF-E20AFD1AE70AQ34410500-C0D30FB7-C4CD-44C0-B478-3BE73BA62459Q34438593-2309D92B-FF70-4318-B9D4-251E1717E875Q35037986-219BE148-C775-4615-B779-799FB26F8179Q36458386-755422E2-88D0-4FEB-A74F-7D92351B8BF6Q36545633-73962656-6634-4C34-8FAB-D45473172CE8Q37464073-6BDB5A45-3711-4F86-B8F4-F6C78633F3F5Q38542150-18A45365-09D7-4810-939E-3772C8F2F886Q39018519-FD01FDB3-E7F5-41C0-BE88-2BE56605AA7DQ41529585-47D5A83C-3BA9-460E-851D-ED90E7DB5420Q41932078-FCF049BD-5918-4C5C-8E24-C84328F088FDQ42197171-3686F733-F9AE-4150-863E-DA8312F59745Q47988257-A2893F6E-D9A5-4926-BF1E-EB783973A037Q48823803-80578C88-B972-4807-99E5-44175ACEEDEB
P2860
Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Missense mutations in the huma ...... intrinsic enzymatic function.
@ast
Missense mutations in the huma ...... intrinsic enzymatic function.
@en
type
label
Missense mutations in the huma ...... intrinsic enzymatic function.
@ast
Missense mutations in the huma ...... intrinsic enzymatic function.
@en
prefLabel
Missense mutations in the huma ...... intrinsic enzymatic function.
@ast
Missense mutations in the huma ...... intrinsic enzymatic function.
@en
P2093
P2860
P356
P1433
P1476
Missense mutations in the huma ...... intrinsic enzymatic function.
@en
P2093
Chunzhang Yang
Donald Y Ye
Joey C Matro
Kristin M Huntoon
Stephanie M J Fliedner
Thanh T Huynh
Zhengping Zhuang
P2860
P304
P356
10.1096/FJ.12-210146
P407
P50
P577
2012-07-26T00:00:00Z