MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein.
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FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarctionTherapeutic targets in the ASK1-dependent stress signaling pathwaysTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerStructure-Activity Relationships and X-ray Structures Describing the Selectivity of Aminopyrazole Inhibitors for c-Jun N-terminal Kinase 3 (JNK3) over p38Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) InhibitorsIL-13-induced airway mucus production is attenuated by MAPK13 inhibition.Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitorIdentification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growthNovel druggable hot spots in avian influenza neuraminidase H5N1 revealed by computational solvent mapping of a reduced and representative receptor ensemble.The p38alpha mitogen-activated protein kinase as a central nervous system drug discovery target.Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitro.The potential of p38 MAPK inhibitors to modulate periodontal infections.Inhibition of the p38 kinase suppresses the proliferation of human ER-negative breast cancer cellsIdentification of genomic targets downstream of p38 mitogen-activated protein kinase pathway mediating tumor necrosis factor-alpha signaling.Molecular interaction studies using microscale thermophoresis.p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activationVirtual screening using a conformationally flexible target protein: models for ligand binding to p38α MAPK.Drugs and their molecular targets: an updated overview.An inhibition of p38 mitogen activated protein kinase delays the platelet storage lesion.Exploring kinase inhibitors as therapies for human arenavirus infections.Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare MutationsThe p38 mitogen-activated protein kinase signaling cascade in CD4 T cells.Novel therapies for rheumatoid arthritis.p38 pathway kinases as anti-inflammatory drug targets.Mitogen-activated protein kinases in heart development and diseasesTreatment with histone deacetylase inhibitor attenuates MAP kinase mediated liver injury in a lethal model of septic shock.Identifying targets for COPD treatment through gene expression analyses.The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer.Targeting signaling pathways with small molecules to treat autoimmune disorders.p38α mitogen-activated protein kinase inhibitors, a patent review (2005-2011).Critical review of p38 MAP kinase inhibitors: a bioanalytical perspective.Mitogen-activated protein kinases as therapeutic targets for rheumatoid arthritis.Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases.p38 MAPK inhibitors: a patent review (2012 - 2013).Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer.Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.Fullerenes and their derivatives as inhibitors of tumor necrosis factor-α with highly promoted affinities.
P2860
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P2860
MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@ast
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@en
type
label
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@ast
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@en
prefLabel
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@ast
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@en
P1476
MAP kinase p38 inhibitors: cli ...... actions with p38alpha protein.
@en
P2093
Celia Dominguez
Matthew R Lee
P304
P356
10.2174/092986705774462914
P577
2005-01-01T00:00:00Z