Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.
about
Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agentsThe Role of Histone Acetyltransferases in Normal and Malignant HematopoiesisPost-translational modifications of rat liver mitochondrial outer membrane proteins identified by mass spectrometryRepetitive busulfan administration after hematopoietic stem cell gene therapy associated with a dominant HDAC7 clone in a nonhuman primate.Belinostat, a potent HDACi, exerts antileukaemic effect in human acute promyelocytic leukaemia cells via chromatin remodelling.Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling.Epigenetic regulation of normal and malignant hematopoiesis.Glucose metabolism as a target of histone deacetylase inhibitors.The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemiaMetabolic alterations in cancer cells and therapeutic implications.Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy.Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia.In Vitro Characterization of Valproic Acid, ATRA, and Cytarabine Used for Disease-Stabilization in Human Acute Myeloid Leukemia: Antiproliferative Effects of Drugs on Endothelial and Osteoblastic Cells and Altered Release of Angioregulatory MediatorIncreased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia.The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias.Chromatin context dominates estrogen regulation of pS2 gene expression.The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells.Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid.Combination of the histone deacetylase inhibitor valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe and effective in patients with advanced acute myeloid leukaemia--a report of five cases.Histone deacetylase inhibitor BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells.
P2860
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P2860
Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
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2006年學術文章
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name
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@ast
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@en
type
label
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@ast
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@en
prefLabel
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@ast
Protein lysine acetylation in ...... rapeutic targets in adult AML.
@en
P2093
P2860
P356
P1476
Protein lysine acetylation in ...... erapeutic targets in adult AML
@en
P2093
Anita Ryningen
Camilla Stapnes
Nina Anensen
Øystein Bruserud
P2860
P356
10.1517/14728222.10.1.51
P407
P577
2006-02-01T00:00:00Z