EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
about
The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specializationDistinct domains of paracingulin are involved in its targeting to the actin cytoskeleton and regulation of apical junction assemblyShared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeabilityThe dynamic role of beta-catenin in synaptic plasticityXin proteins and intercalated disc maturation, signaling and diseasesAlterations of the cytoskeleton in human cells in space proved by life-cell imaging.Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesisCRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesisForce dependent biotinylation of myosin IIA by α-catenin tagged with a promiscuous biotin ligaseα-Catenin-mediated cadherin clustering couples cadherin and actin dynamics.Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationControl of cell-cell forces and collective cell dynamics by the intercellular adhesome.The Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network DynamicsDimer asymmetry defines α-catenin interactionsAn Autoinhibited Structure of -Catenin and Its Implications for Vinculin Recruitment to Adherens JunctionsThe Cytoskeletal Protein -Catenin Unfurls upon Binding to VinculinStructural and Thermodynamic Characterization of Cadherin{middle dot} -Catenin{middle dot} -Catenin Complex FormationE-cadherin roles in animal biology: A perspective on thyroid hormone-influenceN-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during developmentActin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctionsOverexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctionsEpithelial junctions and Rho family GTPases: the zonular signalosome.Intercalated disc protein, mXinα, suppresses p120-catenin-induced branching phenotype via its interactions with p120-catenin and cortactinResponses to cell loss become restricted as the supporting cells in mammalian vestibular organs grow thick junctional actin bands that develop high stabilityE-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretchα-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junctionNanomechanics of the cadherin ectodomain: "canalization" by Ca2+ binding results in a new mechanical element.Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interactionPhosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation.A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension.Binding to F-actin guides cadherin cluster assembly, stability, and movement.α-Catenin is an inhibitor of transcription.Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers.Apical constriction: themes and variations on a cellular mechanism driving morphogenesisVascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells.Nanoscale architecture of cadherin-based cell adhesions.The catenin family at a glance.AlphaE-catenin regulates actin dynamics independently of cadherin-mediated cell-cell adhesion.Adenoma formation following limited ablation of p120-catenin in the mouse intestine.
P2860
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P2860
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
EPLIN mediates linkage of the ...... the circumferential actin belt
@ast
EPLIN mediates linkage of the ...... the circumferential actin belt
@en
type
label
EPLIN mediates linkage of the ...... the circumferential actin belt
@ast
EPLIN mediates linkage of the ...... the circumferential actin belt
@en
prefLabel
EPLIN mediates linkage of the ...... the circumferential actin belt
@ast
EPLIN mediates linkage of the ...... the circumferential actin belt
@en
P2860
P356
P1476
EPLIN mediates linkage of the ...... the circumferential actin belt
@en
P2093
Kentaro Abe
P2860
P356
10.1073/PNAS.0710504105
P407
P577
2007-12-18T00:00:00Z