Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome
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Microphysiological Human Brain and Neural Systems-on-a-Chip: Potential Alternatives to Small Animal Models and Emerging Platforms for Drug Discovery and Personalized Medicine.Correlation and Comparison of Cortical and Hippocampal Neural Progenitor Morphology and Differentiation through the Use of Micro- and Nano-Topographies.Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse modelsPatient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment.Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder.Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling.
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Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome
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2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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name
Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
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Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
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type
label
Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
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Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
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prefLabel
Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
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Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
@en
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P2860
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Human iPS Cell-Derived Neurons ...... Signaling in Costello Syndrome
@en
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Alice F Goodwin
Amnon Sharir
Claude M Schofield
Gemma E Rooney
Jeroen P Roose
Katherine A Rauen
Lauren A Weiss
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P304
P356
10.1523/JNEUROSCI.1547-15.2016
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P577
2016-01-01T00:00:00Z