Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication.
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A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cellsPotential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsStress granules in the viral replication cycleIntrinsic Cellular Defenses against Virus Infection by Antiviral Type I InterferonHerpes simplex virus 2 infection impacts stress granule accumulationRespiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replicationIdentification of a novel shrimp protein phosphatase and its association with latency-related ORF427 of white spot syndrome virus.Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein.Up to four distinct polypeptides are produced from the γ34.5 open reading frame of herpes simplex virus 2Structure and sequence of the saimiriine herpesvirus 1 genome.2-aminopurine enhances the oncolytic activity of an E1b-deleted adenovirus in hepatocellular carcinoma cells.ICP34.5 protein of herpes simplex virus facilitates the initiation of protein translation by bridging eukaryotic initiation factor 2alpha (eIF2alpha) and protein phosphatase 1Replication of herpes simplex virus 1 depends on the gamma 134.5 functions that facilitate virus response to interferon and egress in the different stages of productive infection.Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes.The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR.Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells.Effect of γ34.5 deletions on oncolytic herpes simplex virus activity in brain tumors.Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1.Herpes simplex virus 2 expresses a novel form of ICP34.5, a major viral neurovirulence factor, through regulated alternative splicing.Spread and replication of and immune response to gamma134.5-negative herpes simplex virus type 1 vectors in BALB/c mice.HSV Recombinant Vectors for Gene Therapy.Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response.Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state.The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products.The Role of Herpes Simplex Virus Type 1 γ34.5 in the Regulation of IRF3 Signaling.Involvement of herpes simplex virus type 1 UL13 protein kinase in induction of SOCS genes, the negative regulators of cytokine signaling.Persistent borna disease virus infection confers instability of HSP70 mRNA in glial cells during heat stress.Increased eIF2alpha phosphorylation attenuates replication of herpes simplex virus 2 vhs mutants in mouse embryonic fibroblasts and correlates with reduced accumulation of the PKR antagonist ICP34.5.Understanding Primate Herpesviruses
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Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication.
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2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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name
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@ast
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@en
type
label
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@ast
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@en
prefLabel
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@ast
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@en
P2093
P2860
P1433
P1476
Dephosphorylation of eIF-2alph ...... r efficient viral replication.
@en
P2093
P2860
P304
10154-10161
P356
10.1128/JVI.77.18.10154-10161.2003
P407
P577
2003-09-01T00:00:00Z