Dominant transformation by mutated human ras genes in vitro requires more than 100 times higher expression than is observed in cancers
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How aneuploidy affects metabolic control and causes cancerGenetic instability of cancer cells is proportional to their degree of aneuploidyReplacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responsesFunctional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator PhenotypeAneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.Molecular techniques for studying gene expression in carcinogenesis.CArG binding factor A (CBF-A) is involved in transcriptional regulation of the rat Ha-ras promoter.Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras.c-Ki-ras mutations in colorectal adenocarcinomas from a country with a rapidly changing colorectal cancer incidence.Aneuploidy correlated 100% with chemical transformation of Chinese hamster cells.Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.PI3-kinase p85alpha is a target molecule of proline-rich antimicrobial peptide to suppress proliferation of ras-transformed cells.Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.Will we cure cancer by sequencing thousands of genomes?Aneuploidy and cancer: vintage wine in a new bottle?Gene expression patterns and cancer
P2860
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P2860
Dominant transformation by mutated human ras genes in vitro requires more than 100 times higher expression than is observed in cancers
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Dominant transformation by mut ...... on than is observed in cancers
@ast
Dominant transformation by mut ...... on than is observed in cancers
@en
type
label
Dominant transformation by mut ...... on than is observed in cancers
@ast
Dominant transformation by mut ...... on than is observed in cancers
@en
prefLabel
Dominant transformation by mut ...... on than is observed in cancers
@ast
Dominant transformation by mut ...... on than is observed in cancers
@en
P2093
P2860
P356
P1476
Dominant transformation by mut ...... on than is observed in cancers
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.18.9614
P407
P577
1997-09-01T00:00:00Z