Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
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mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infectionUpstream open reading frames: molecular switches in (patho)physiologyNesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistanceCharacterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1Human eukaryotic release factor 3a depletion causes cell cycle arrest at G1 phase through inhibition of the mTOR pathwayA unifying theory for general multigenic heterosis: energy efficiency, protein metabolism, and implications for molecular breedingmTOR: a potential therapeutic target in osteoarthritis?p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signalingDEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagyFisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factorsThe tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptakeTarget Of Rapamycin (TOR) SignalingMultiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.Everolimus for compassionate use in multiple Basal cell carcinomas.Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cellsPRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.Local translation in primary afferent fibers regulates nociceptionOral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.Evaluation of everolimus in renal cell cancer.Discovery of chemical modulators of a conserved translational control pathway by parallel screening in yeast.The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cellsPhysiological regulation of Akt activity and stability.Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cellsPKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.Regulation of 4E-BP1 activity in the mammalian oocyte.Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinaseInduction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.Role of inositol trisphosphate receptors in autophagy in DT40 cells.Regulation of mTORC1 signaling by pHA gene-alteration profile of human lung cancer cell lines.Genomewide analysis of inherited variation associated with phosphorylation of PI3K/AKT/mTOR signaling proteinsDysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunitiesThe complement cascade as a mediator of tissue growth and regeneration.Virus-mediated compartmentalization of the host translational machinery.Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation.Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphateThe order of exercise during concurrent training for rehabilitation does not alter acute genetic expression, mitochondrial enzyme activity or improvements in muscle functionThe abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.Everolimus - a new approach in the treatment of renal cell carcinomaDEPTOR is a stemness factor that regulates pluripotency of embryonic stem cells
P2860
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P2860
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@ast
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@en
type
label
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@ast
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@en
prefLabel
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@ast
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@en
P356
P1433
P1476
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
@en
P2093
Corradetti MN
P2888
P304
P356
10.1038/SJ.ONC.1209885
P407
P577
2006-10-01T00:00:00Z
P5875
P6179
1041873995