A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.
about
Androgen receptor molecular biology and potential targets in prostate cancerDiscovery of selective inhibitors against EBNA1 via high throughput in silico virtual screeningIn search of novel drug target sites on estrogen receptors using RNA aptamers.Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs)Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.Differential requirements of Hsp90 and DNA for the formation of estrogen receptor homodimers and heterodimers.CBP mediates NF-κB-dependent histone acetylation and estrogen receptor recruitment to an estrogen response element in the BIRC3 promoter.Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements.Noncanonical mechanisms to regulate nuclear receptor signaling.Selectively targeting estrogen receptors for cancer treatment.A noncompetitive small molecule inhibitor of estrogen-regulated gene expression and breast cancer cell growth that enhances proteasome-dependent degradation of estrogen receptor {alpha}.Small molecule inhibitors as probes for estrogen and androgen receptor actionHigh-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genesAllosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.Antiestrogen Resistant Cell Lines Expressing Estrogen Receptor α Mutations Upregulate the Unfolded Protein Response and are Killed by BHPI.Direct interdomain interactions can mediate allosterism in the thyroid receptorDesigner monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.Minireview: dynamic structures of nuclear hormone receptors: new promises and challenges.Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.8-alkylthio-6-thio-substituted theophylline analogues as selective noncompetitive progesterone receptor antagonists.Genomic responses from the estrogen-responsive element-dependent signaling pathway mediated by estrogen receptor alpha are required to elicit cellular alterations.Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements.A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation.Fluorescence anisotropy microplate assay to investigate the interaction of full-length steroid receptor coactivator-1a with steroid receptors.
P2860
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P2860
A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A new small molecule inhibitor ...... endent growth of cancer cells.
@ast
A new small molecule inhibitor ...... endent growth of cancer cells.
@en
type
label
A new small molecule inhibitor ...... endent growth of cancer cells.
@ast
A new small molecule inhibitor ...... endent growth of cancer cells.
@en
prefLabel
A new small molecule inhibitor ...... endent growth of cancer cells.
@ast
A new small molecule inhibitor ...... endent growth of cancer cells.
@en
P2093
P2860
P356
P1476
A new small molecule inhibitor ...... endent growth of cancer cells.
@en
P2093
Ann M Nardulli
Chen Zhang
Chengjian Mao
David J Shapiro
Elizabeth M Wilson
Irene O Aninye
Jamie Bonéy Montoya
Jingwei Cheng
Karson S Putt
Milu T Cherian
P2860
P304
12819-12830
P356
10.1074/JBC.M709936200
P407
P577
2008-03-12T00:00:00Z