Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells
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Molecular regulation of NKCC2 in the thick ascending limbMolecular and evolutionary insights into the structural organization of cation chloride cotransportersMolecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.Rare mutations in renal sodium and potassium transporter genes exhibit impaired transport function.Secretory carrier membrane protein 2 regulates exocytic insertion of NKCC2 into the cell membrane.MAL/VIP17, a new player in the regulation of NKCC2 in the kidneyHigh-throughput fluorescent-based NKCC functional assay in adherent epithelial cells.Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function.Cation-chloride cotransporters in neuronal development, plasticity and diseaseFunctional expression of human NKCC1 from a synthetic cassette-based cDNA: introduction of extracellular epitope tags and removal of cysteines.Impact of Hybrid and Complex N-Glycans on Cell Surface Targeting of the Endogenous Chloride Cotransporter Slc12a2.Loop diuretic and ion-binding residues revealed by scanning mutagenesis of transmembrane helix 3 (TM3) of Na-K-Cl cotransporter (NKCC1)Molecular and functional expression of cation-chloride cotransporters in dorsal root ganglion neurons during postnatal maturationNKCC1 knockdown decreases neuron production through GABA(A)-regulated neural progenitor proliferation and delays dendrite development.Real-time monitoring of NKCC2 endocytosis by total internal reflection fluorescence (TIRF) microscopy.The absence of a clathrin adapter confers unique polarity essential to proximal tubule functionA patient with multisystem dysfunction carries a truncation mutation in human SLC12A2, the gene encoding the Na-K-2Cl cotransporter, NKCC1.Physiology and pathophysiology of SLC12A1/2 transporters.Polarized traffic towards the cell surface: how to find the route.Na+-K+-2Cl- cotransporter type 2 trafficking and activity: the role of interacting proteins.NKCC2 activity is inhibited by the Bartter's syndrome type 5 gain-of-function CaR-A843E mutant in renal cells.Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells.Directional Fluid Transport across Organ-Blood Barriers: Physiology and Cell Biology.A highly conserved motif at the COOH terminus dictates endoplasmic reticulum exit and cell surface expression of NKCC2.Nkcc1 (Slc12a2) is required for the regulation of endolymph volume in the otic vesicle and swim bladder volume in the zebrafish larva.Evolution of the cation chloride cotransporter family: ancient origins, gene losses, and subfunctionalization through duplication.Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking.NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension.Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B.
P2860
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P2860
Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Exon loss accounts for differe ...... in polarized epithelial cells
@en
type
label
Exon loss accounts for differe ...... in polarized epithelial cells
@en
prefLabel
Exon loss accounts for differe ...... in polarized epithelial cells
@en
P2860
P356
P1476
Exon loss accounts for differe ...... in polarized epithelial cells
@en
P2093
Biff Forbush
Michael Caplan
P2860
P304
P356
10.1091/MBC.E08-05-0478
P577
2008-07-30T00:00:00Z